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Paid Clinical Trials Detroit

Discover 1,725 paid clinical trials in Detroit, Michigan. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Detroit MI, Cleveland OH, Hamilton, Toronto, Barrie,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase 3, Recruiting

ICG Fluorescence in Knee Arthroscopy Study

for
To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion,
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 14 - 70+

Code: NCT07793266

Phase 1, Recruiting

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

for
Acute Respiratory Distress Syndrome, ARDS
Location: Detroit MI, Cleveland OH, Silver Spring MD,
Sponsor: Direct Biologics, LLC

Sex: All

Age: 18 - 70+

Code: NCT05354141

Phase 3, Recruiting

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

for
Coronavirus Infection, Severe Acute Respiratory Infection,
Location: Detroit MI, Chicago IL, Bethesda MD, Washington DC,
Sponsor: Biomed Industries, Inc.

Sex: All

Age: 18 - 70+

Code: NCT04452565

Phase 2, Phase 3, Recruiting

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

for
Amyotrophic Lateral Sclerosis (ALS)
Location: Detroit MI, Pittsburgh PA, Richmond VA,
Sponsor: Zydus Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07023835

Phase 2, Recruiting

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A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for
Relapsing Multiple Sclerosis, Multiple Sclerosis
Location: Detroit MI, Farmington MI, Rochester Hills MI,
Sponsor: TG Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06433752

Recruiting

Understanding Pathways to Wellness and Recovery in Detroit - Digital Recovery Support Services

for
Alcohol Use Disorder, Recovery Outcomes, Digital Health
Location: Detroit MI
Sponsor: Brandeis University

Sex: All

Age: 18+

Code: NCT07724275

Recruiting

Peer-Delivered Behavioral Activation in a CCBHC

for
Major Depressive Disorder, Substance Use Disorders
Location: Detroit MI
Sponsor: Wayne State University

Sex: All

Age: 18+

Code: NCT07219394

Recruiting

Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Detroit MI, Ann Arbor MI, Montreal, Deerfield Beach FL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06057402

Recruiting

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

for
Breast Cancer
Location: Detroit MI, Grand Rapids MI, Big Rapids MI, Holland MI,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07062965

Phase 3, Recruiting

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

for
Advanced Solid Tumor
Location: Detroit MI, Cleveland OH, Grand Rapids MI,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07070232

Phase 1, Phase 2, Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for
Breast Neoplasms
Location: Detroit MI, Winchester VA, Decatur IL, Allentown PA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06926868

Phase 2, Phase 3, Recruiting

Community Based Treatment for (ComBaT) Glaucoma

for
Glaucoma
Location: Detroit MI
Sponsor: University of Michigan

Sex: All

Age: 40+

Code: NCT06124521

Recruiting

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer,
Location: Detroit MI, Cleveland OH, Hamilton, Toronto, Buffalo NY,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06343402

Phase 1, Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for
Advanced Melanoma
Location: Detroit MI, Columbus OH, Toronto, Pittsburgh PA,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT06112314

Phase 3, Recruiting

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for
Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis,
Location: Detroit MI, Ann Arbor MI, Cleveland OH, Independence OH,
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06479135

Phase 3, Recruiting

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

for
Solid Tumor, Adult, Metastatic Solid Tumor, Refractory Cancer,
Location: Detroit MI, Canton OH, Fairfax VA, St Louis MO,
Sponsor: Sairopa B.V.

Sex: All

Age: 18+

Code: NCT05856981

Phase 1, Recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Detroit MI, Ann Arbor MI, Cleveland OH, London,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase 3, Recruiting

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

for
Locally Advanced Solid Tumor
Location: Detroit MI, Chicago IL, Zion IL, Urbana IL, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05732831

Phase 1, Phase 2, Recruiting

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Detroit MI, Columbus OH, Toronto, Chicago IL,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05384626

Phase 1, Phase 2, Recruiting