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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for
Rheumatoid Arthritis
Location: Charlotte NC, Summerville SC, Jacksonville FL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06972446

Phase2, Recruiting
FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for
Moderately to Severely Active Ulcerative Colitis
Location: Charlotte NC, High Point NC, Greenville SC, Roanoke VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06588855

Phase3, Recruiting
FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Charlotte NC, Monroe NC, Greenville SC, Roanoke VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase3, Recruiting
Featured

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07555938

Phase3, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Charlotte NC, Winston-Salem NC, Atlanta GA, Norfolk VA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase1, Phase2, Recruiting

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Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Charlotte NC, Winston-Salem NC, Greenville SC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Charlotte NC, High Point NC, Atlanta GA, Richmond VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Charlotte NC, Philadelphia PA, Germantown TN, Boston MA,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT04802759

Phase1, Phase2, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06953960

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Charlotte NC, Washington D.C. DC, Hyattsville MD,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05894239

Phase3, Recruiting
Featured

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for
Migraine
Location: Charlotte NC, Greenville SC, Atlanta GA, Savannah GA,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05125302

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Featured

A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for
Advanced Squamous Tumors
Location: Huntersville NC, Chicago IL, Toronto, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07241039

Phase1, Recruiting
FeaturedNew

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: Monroe NC, Greensboro NC, Danville VA, Bristol TN,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

for
Ulcerative Colitis
Location: Monroe NC, Kissimmee FL, Fresh Meadows NY, Chicago IL,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT06979336

Phase2, Recruiting
Featured

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

for
Neovascular Age-related Macular Degeneration
Location: Hickory NC, Austin TX
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT04853251

Recruiting
Active & ResponsiveNew

Leveraging Chatbot to Improve PrEP in the Southern United States

for
HIV Prevention, PrEP Awareness, PrEP Uptake
Location: Charlotte NC, Atlanta GA, Pembroke Pines FL, Miami FL
Sponsor: Yale University

Sex: Male

Age: 18+

Code: NCT05968755

Recruiting
Active & Responsive

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for
Generalized Myasthenia Gravis
Location: Charlotte NC, Chapel Hill NC, Durham NC, Augusta GA,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT04202341

Recruiting