Discover 646 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Charlotte offers many opportunities to participate in clinical research focused on various conditions, including cancer, lymphoma, heart disease, and cystic fibrosis. The city’s medical research institutions are recruiting both healthy volunteers interested in paid trials, as well as individuals with specific health conditions.
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Results: 646
FeaturedActive & Responsive
Weight Loss Studies for Adults With a BMI of 27+, Including People Managing Type 2 Diabetes or Sleep Apnea
for
Obesity, Overweight, Diabetes Mellitus, Type 2,
Location: Monroe NC, Gaffney SC, Durham NC, New Bern NC,
Sex: All
Age: 18+
Recruiting
FeaturedActive & Responsive
Crohn's Disease and Ulcerative Colitis Studies for Adults With Hard-to-Treat Symptoms
Location: Monroe NC, Gaffney SC, Union SC, Mauldin SC, Durham NC,
Sex: All
Age: 18+
Recruiting
FeaturedActive & Responsive
Type 2 Diabetes Studies on Blood Sugar and Weight Management for Adults Not on Insulin
for
Diabetes Mellitus, Type 2, Obesity
Location: Gaffney SC, Anderson SC, Durham NC, Charleston SC,
Sex: All
Age: 18 - 70+
Recruiting
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FeaturedActive & Responsive
COPD, Emphysema, and Chronic Bronchitis Studies for Current or Former Smokers
for
Pulmonary Disease, Chronic Obstructive
Location: Gaffney SC, Union SC, Spartanburg SC, Columbia SC,
Sex: All
Age: 40 - 70+
Recruiting
Active & Responsive
Leveraging Chatbot to Improve PrEP in the Southern United States
for
HIV Prevention, PrEP Awareness, PrEP Uptake
Location: Charlotte NC, Atlanta GA, Pembroke Pines FL, Miami FL
Sponsor: Yale University
Sex: Male
Age: 18+
Code: NCT05968755
Recruiting
Active & Responsive
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)
for
Generalized Myasthenia Gravis
Location: Charlotte NC, Chapel Hill NC, Durham NC, Augusta GA,
Sponsor: Alexion Pharmaceuticals, Inc.
Sex: All
Age: 18+
Code: NCT04202341
Recruiting
Active & ResponsiveNew
A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations
for
SARS-CoV-2
Location: Charlotte NC, Hendersonville TN, Louisville KY,
Sponsor: ModernaTX, Inc.
Sex: All
Age: 12+
Code: NCT07863635
Phase 4, Recruiting
Active & Responsive
The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps
for
Poor Sleep Quality, Leg Cramps, Nocturnal, Melatonin, Magnesium,
Location: Charlotte NC, Charleston SC, Atlanta GA, Nashville TN,
Sponsor: StudySetGo
Sex: All
Age: 40 - 70+
Code: NCT07651514
Recruiting
Active & Responsive
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
for
NASH - Nonalcoholic Steatohepatitis,
Location: Charlotte NC, Statesville NC, Columbia SC,
Sponsor: Akero Therapeutics, Inc
Sex: All
Age: 18 - 70+
Code: NCT06528314
Phase 3, Recruiting
Active & Responsive
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
for
NASH With Fibrosis, MASH With Fibrosis
Location: Charlotte NC, Statesville NC, Fayetteville NC,
Sponsor: Akero Therapeutics, Inc
Sex: All
Age: 18 - 70+
Code: NCT06215716
Phase 3, Recruiting
Active & Responsive
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Charlotte NC, Matthews NC, Huntersville NC,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 18+
Code: NCT07091617
Recruiting
Active & Responsive
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
for
CLL/SLL
Location: Charlotte NC, Jacksonville FL, Canton OH, Cleveland OH,
Sponsor: Ascentage Pharma Group Inc.
Sex: All
Age: 18 - 70+
Code: NCT04215809
Phase 1, Recruiting
Active & Responsive
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
for
Percutaneous Coronary Intervention,
Location: Charlotte NC, Winston-Salem NC, High Point NC,
Sponsor: Duke University
Sex: All
Age: 18+
Code: NCT06909565
Phase 4, Recruiting
Active & Responsive
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
for
Carcinoma, Non-Small-Cell Lung
Location: Charlotte NC, Winston-Salem NC, Knoxville TN,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06623422
Phase 3, Recruiting
Active & Responsive
Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections
for
Periprosthetic Joint Infection
Location: Charlotte NC, Durham NC, Lansing MI
Sponsor: OsteoRemedies, LLC
Sex: All
Age: 21+
Code: NCT06428448
Phase 2, Recruiting
Active & Responsive
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
for
Knee Cartilage Defects
Location: Charlotte NC, Morehead City NC, Lexington KY,
Sponsor: Medipost, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07339111
Phase 3, Recruiting
Active & Responsive
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
for
Primary Sjogren's Disease
Location: Charlotte NC, Durham NC, Chesapeake VA, Rockville MD,
Sponsor: Vor Biopharma
Sex: All
Age: 18 - 70+
Code: NCT07404865
Phase 3, Recruiting
Active & Responsive
Pivotal Study of the Velocity™ pAVF System
for
Chronic Kidney Disease, Hemodialysis Access,
Location: Charlotte NC, Orangeburg SC, Jacksonville FL, Dothan AL,