Clinical Trials In Charlotte

Discover hundreds of clinical trials in Charlotte.
Search clinical trials in Charlotte by condition or phase.

e.g. Respiratory Diseases

Charlotte•Healthy volunteers: No

Filter results

Results: 713

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Recruiting

Sponsor:

NRG Oncology

Location:

Reidsville, Greensboro, Burlington, Asheboroshow 358 more

Code:

NCT05896189

Conditions

Breast Cancer

Cognitive Impairments

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Arm 1: Computerized Cognitive Training-Global Stimulation Games

Arm 2: Computerized Cognitive Training-Neuroplasticity Games

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

Recruiting

Phase 2

Phase 3

Sponsor:

Takeda

Location:

Huntersville, Denver, Birmingham, Redwood Cityshow 14 more

Code:

NCT05816382

Conditions

Narcolepsy Type 1

Eligibility Criteria

Sex: All

Age: 16 - 70

Healthy Volunteers: Not accepted

Interventions

TAK-861

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Recruiting

Sponsor:

Abbott Medical Devices

Location:

Charlotte, Asheville, Birmingham, Phoenixshow 60 more

Code:

NCT03433274

Conditions

Mitral Regurgitation

Mitral Insufficiency

Mitral Valve Insufficiency

Cardiovascular Diseases

Valve Disease, Heart

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tendyne Mitral Valve System

MitraClip System

Enhancing Wellness Through Affirming Services and Education

Recruiting

Sponsor:

Duke University

Location:

Charlotte

Code:

NCT05700474

Conditions

HIV

Mental Health Disorder

Substance Use

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Comprehensive outpatient behavioral health care

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Recruiting

Phase 3

Sponsor:

Major Extremity Trauma Research Consortium

Location:

Charlotte, Winston-Salem, Indianapolis, Baltimoreshow 7 more

Code:

NCT05699174

Conditions

Infections

Infected Wound

Nonunion of Fracture

Injury Leg

Amputation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Standard of Care PO (oral) antibiotics

Standard of Care Intravenous (IV) antibiotics

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

Recruiting

Phase 2

Sponsor:

Uniquity One (UNI)

Location:

Winston-Salem, Wilmington, High Point, Gastoniashow 21 more

Code:

NCT06496620

Conditions

COPD

Eligibility Criteria

Sex: All

Age: 40 - 70

Healthy Volunteers: Not accepted

Interventions

Biological: Solrikitug low dose

Biological: Solrikitug high dose

Placebo

Harmony TPV Post-Approval Study

Recruiting

Sponsor:

Medtronic Cardiovascular

Location:

Charlotte, Durham, Birmingham, Phoenixshow 16 more

Code:

NCT05077774

Conditions

Congenital Heart Disease

Tetrology of Fallot

RVOT Anomaly

Pulmonary Regurgitation

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Harmony TPV System

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Recruiting

Phase 2

Sponsor:

Amgen

Location:

Charlotte, Glendale, Mesa, Napashow 12 more

Code:

NCT06312020

Conditions

Sjogren's Syndrome

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

HZN-1116

Placebo

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Recruiting

Phase 3

Sponsor:

Eli Lilly and Company

Location:

Winston-Salem, Statesville, Monroe, Birminghamshow 74 more

Code:

NCT04396574

Conditions

Migraine

Eligibility Criteria

Sex: All

Age: 6 - 17

Healthy Volunteers: Not accepted

Interventions

Lasmiditan

Study of XB010 in Subjects With Solid Tumors

Recruiting

Phase 1

Sponsor:

Exelixis

Location:

Huntersville, Austin, Fairfax

Code:

NCT06545331

Conditions

Locally Advanced or Metastatic Solid Tumors

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

XB010

Pembrolizumab

e.g. Respiratory Diseases

Charlotte•Healthy volunteers: No

Filter results

Results: 713

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Recruiting

Sponsor:

NRG Oncology

Location:

Reidsville, Greensboro, Burlington, Asheboroshow 358 more

Code:

NCT05896189

Conditions

Breast Cancer

Cognitive Impairments

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Arm 1: Computerized Cognitive Training-Global Stimulation Games

Arm 2: Computerized Cognitive Training-Neuroplasticity Games

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

Recruiting

Phase 2

Phase 3

Sponsor:

Takeda

Location:

Huntersville, Denver, Birmingham, Redwood Cityshow 14 more

Code:

NCT05816382

Conditions

Narcolepsy Type 1

Eligibility Criteria

Sex: All

Age: 16 - 70

Healthy Volunteers: Not accepted

Interventions

TAK-861

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Recruiting

Sponsor:

Abbott Medical Devices

Location:

Charlotte, Asheville, Birmingham, Phoenixshow 60 more

Code:

NCT03433274

Conditions

Mitral Regurgitation

Mitral Insufficiency

Mitral Valve Insufficiency

Cardiovascular Diseases

Valve Disease, Heart

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tendyne Mitral Valve System

MitraClip System

Enhancing Wellness Through Affirming Services and Education

Recruiting

Sponsor:

Duke University

Location:

Charlotte

Code:

NCT05700474

Conditions

HIV

Mental Health Disorder

Substance Use

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Comprehensive outpatient behavioral health care

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Recruiting

Phase 3

Sponsor:

Major Extremity Trauma Research Consortium

Location:

Charlotte, Winston-Salem, Indianapolis, Baltimoreshow 7 more

Code:

NCT05699174

Conditions

Infections

Infected Wound

Nonunion of Fracture

Injury Leg

Amputation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Standard of Care PO (oral) antibiotics

Standard of Care Intravenous (IV) antibiotics

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

Recruiting

Phase 2

Sponsor:

Uniquity One (UNI)

Location:

Winston-Salem, Wilmington, High Point, Gastoniashow 21 more

Code:

NCT06496620

Conditions

COPD

Eligibility Criteria

Sex: All

Age: 40 - 70

Healthy Volunteers: Not accepted

Interventions

Biological: Solrikitug low dose

Biological: Solrikitug high dose

Placebo

Harmony TPV Post-Approval Study

Recruiting

Sponsor:

Medtronic Cardiovascular

Location:

Charlotte, Durham, Birmingham, Phoenixshow 16 more

Code:

NCT05077774

Conditions

Congenital Heart Disease

Tetrology of Fallot

RVOT Anomaly

Pulmonary Regurgitation

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Harmony TPV System

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Recruiting

Phase 2

Sponsor:

Amgen

Location:

Charlotte, Glendale, Mesa, Napashow 12 more

Code:

NCT06312020

Conditions

Sjogren's Syndrome

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

HZN-1116

Placebo

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Recruiting

Phase 3

Sponsor:

Eli Lilly and Company

Location:

Winston-Salem, Statesville, Monroe, Birminghamshow 74 more

Code:

NCT04396574

Conditions

Migraine

Eligibility Criteria

Sex: All

Age: 6 - 17

Healthy Volunteers: Not accepted

Interventions

Lasmiditan

Study of XB010 in Subjects With Solid Tumors

Recruiting

Phase 1

Sponsor:

Exelixis

Location:

Huntersville, Austin, Fairfax

Code:

NCT06545331

Conditions

Locally Advanced or Metastatic Solid Tumors

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

XB010

Pembrolizumab