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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Stroke Thrombectomy and Aneurysm Registry

for
Stroke, Thromboses, Intracranial, Aneurysm, Brain
Location: Raleigh NC, Winston-Salem NC, Charlottesville VA,
Sponsor: Medical University of South Carolina

Sex: All

Age: 1 - 70+

Code: NCT04994756

Recruiting

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

for
Type 2 Diabetes, Cortisol Excess
Location: Chapel Hill NC, Greenville NC, Wilmington NC,
Sponsor: Sparrow Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07296484

Phase2, Recruiting

PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

for
End Stage Renal Disease, Hemodialysis Access Failure
Location: Raleigh NC, Norfolk VA, Washington D.C. DC,
Sponsor: Merit Medical Systems, Inc.

Sex: All

Age: 18+

Code: NCT06422871

Recruiting

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

for
Obesity, Multiple Chronic Conditions
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 65 - 70+

Code: NCT06044571

Recruiting

A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for
Idiopathic Pulmonary Fibrosis (IPF)
Location: Chapel Hill NC, Charleston SC, Cincinnati OH,
Sponsor: Rein Therapeutics

Sex: All

Age: 40+

Code: NCT06968845

Phase2, Recruiting

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DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

for
Refractory Melanoma
Location: Chapel Hill NC, Morristown NJ, Birmingham AL, Boston MA,
Sponsor: Diakonos Oncology Corporation

Sex: All

Age: 18+

Code: NCT07288112

Phase1, Phase2, Recruiting

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

for
Advanced Renal Cell Carcinoma (aRCC),
Location: Chapel Hill NC, Washington D.C. DC, Hershey PA,
Sponsor: Brian Rini

Sex: All

Age: 18+

Code: NCT07188896

Phase2, Recruiting

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

for
Follicular Lymphoma (FL)
Location: Chapel Hill NC, Charlotte NC, Charlottesville VA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06091254

Phase3, Recruiting

A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for
Clinical High Risk for Psychosis (CHR)
Location: Chapel Hill NC, Pittsburgh PA, Philadelphia PA,
Sponsor: Monument Therapeutics Limited

Sex: All

Age: 17 - 30

Code: NCT07226895

Phase1, Phase2, Recruiting

Sitting Interruption and Whole-body Cardiovascular Health

for
Sedentary Behavior, Sedentary Time
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 30 - 60

Code: NCT05316571

Recruiting

Zenith® Fenestrated+ Clinical Study

for
Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm,
Location: Chapel Hill NC, Kingsport TN, Washington D.C. DC,
Sponsor: Cook Research Incorporated

Sex: All

Age: 18+

Code: NCT04875429

Recruiting

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for
Aortic Dissection, Aortic Aneurysm, Intramural Hematoma,
Location: Chapel Hill NC, Roanoke VA, Charlotte NC, Norfolk VA,
Sponsor: Endospan Ltd.

Sex: All

Age: 18+

Code: NCT04471909

Recruiting

Descartes-08 in Autoantibody Myositis

for
Antisynthetase Syndrome
Location: Chapel Hill NC, Boston MA, Austin TX, Orange CA
Sponsor: Cartesian Therapeutics

Sex: All

Age: 18+

Code: NCT07391605

Phase2, Recruiting

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

for
Heart Failure
Location: Raleigh NC, Greensboro NC, Norfolk VA, Manassas VA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT06424288

Phase3, Recruiting

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

for
GIST - Gastrointestinal Stromal Tumor, GIST,
Location: Chapel Hill NC, Philadelphia PA, Cleveland OH,
Sponsor: Kumquat Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07406633

Phase2, Recruiting

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

for
Crohn Disease
Location: Chapel Hill NC, Charlotte NC, Summerville SC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07499232

Phase3, Recruiting

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

for
Hypogammaglobulinemia, Bacterial Infections,
Location: Morrisville NC, Greenville NC, Bethesda MD, Canton OH,
Sponsor: Grifols Therapeutics LLC

Sex: All

Age: 18+

Code: NCT05645107

Phase3, Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

for
Glioblastoma, Recurrent Glioblastoma, GBM
Location: Chapel Hill NC, Baltimore MD, Atlanta GA, Cleveland OH,
Sponsor: CarThera

Sex: All

Age: 18+

Code: NCT05902169

Phase3, Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma (PDAC), G12D Mutated KRAS
Location: Chapel Hill NC, Charlottesville VA, Fairfax VA,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07644559

Phase2, Recruiting

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for
Ovarian Cancer
Location: Chapel Hill NC, Towson MD, Savannah GA, Lancaster PA,
Sponsor: Daiichi Sankyo

Sex: Female

Age: 18+

Code: NCT06819007

Phase3, Recruiting