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Paid Clinical Trials Raleigh

Discover 1,655 paid clinical trials in Raleigh, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy

for
Cytokine Release Syndrome
Location: Durham NC, Augusta GA, Pittsburgh PA, Boston MA,
Sponsor: CytoAgents, Inc.

Sex: All

Age: 18+

Code: NCT05905328

Phase 1, Phase 2, Recruiting

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Breast Cancer,
Location: Durham NC, Columbus OH, Nashville TN, Denver CO,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06120283

Phase 1, Recruiting

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

for
Gastric or Gastroesophageal Junction Adenocarcinoma,
Location: Durham NC, Fairfax VA, Pittsburgh PA, Louisville KY,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05482893

Phase 1, Phase 2, Recruiting

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Durham NC, Winston-Salem NC, Charlotte NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase 3, Recruiting

Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma

for
Solid Tumor, Soft Tissue Sarcoma, Metastatic Sarcoma, Sarcoma
Location: Durham NC, Chapel Hill NC, Santa Monica CA
Sponsor: NanoCarrier Co., Ltd.

Sex: All

Age: 18 - 70+

Code: NCT03168061

Phase 1, Phase 2, Recruiting

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A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for
Colorectal Neoplasms
Location: Durham NC, Pinehurst NC, Roanoke VA, Salem VA,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05253651

Phase 3, Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for
Triple Negative Breast Cancer
Location: Durham NC, Chapel Hill NC, Greensboro NC,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05633654

Phase 3, Recruiting

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for
Non-Small Cell Lung Cancer (NSCLC)
Location: Durham NC, Pinehurst NC, Lancaster SC, Asheville NC,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT05920356

Phase 3, Recruiting

Engage Psychosocial Intervention for Cancer Symptoms

for
Advanced Breast Cancer, Advanced Prostate Cancer,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06555588

Recruiting

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for
Relapsed Hematologic Malignancy,
Location: Durham NC, Pittsburgh PA, Jacksonville FL, Cleveland OH,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT03328078

Phase 1, Phase 2, Recruiting

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for
Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
Location: Durham NC, Charlotte NC, Fairfax VA, Atlanta GA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06765109

Phase 3, Recruiting

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for
T-Cell Neoplasm, Lymphoproliferative Disorders
Location: Durham NC, Columbus OH, Ann Arbor MI, Duarte CA
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT04858256

Phase 2, Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

for
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer,
Location: Durham NC, Fairfax VA, New Brunswick NJ, Cleveland OH,
Sponsor: Iambic Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06253871

Phase 1, Recruiting

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for
Solid Tumors
Location: Durham NC, Spartanburg SC, Fairfax VA,
Sponsor: ORIC Pharmaceuticals

Sex: All

Age: 18+

Code: NCT05315700

Phase 1, Phase 2, Recruiting

A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for
Low-grade Glioma, Advanced Solid Tumor
Location: Durham NC, Washington DC, Philadelphia PA, New York NY,
Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All

Age: 0 - 25

Code: NCT04775485

Phase 2, Recruiting

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

for
Relapsed or Refractory Multiple Myeloma
Location: Durham NC, Roanoke VA, Norfolk VA, Fredericksburg VA,
Sponsor: Celgene

Sex: All

Age: 18+

Code: NCT05519085

Phase 3, Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for
Metastatic Colorectal Cancer
Location: Durham NC, Pikeville KY, Jacksonville FL, Nashville TN,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT06252649

Phase 3, Recruiting

Safety of HRX215 in Patients After Minor and Major Liver Resection

for
Liver Resection, Colorectal Carcinoma Liver Metastases
Location: Durham NC, Baltimore MD, Cleveland OH, Rochester MN
Sponsor: HepaRegeniX GmbH

Sex: All

Age: 18 - 70+

Code: NCT06638502

Phase 1, Phase 2, Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Location: Durham NC, Chapel Hill NC, Richmond VA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06119581

Phase 3, Recruiting

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

for
Hematopoietic Stem Cell Transplant, CAR-T Cell Therapy
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT06575712

Recruiting