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Paid Clinical Trials Cleveland

Discover 1,399 paid clinical trials in Cleveland, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for
Solid Tumors
Location: Cleveland OH, Nashville TN, St Louis MO, Houston TX,
Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All

Age: 18+

Code: NCT06386146

Phase1, Phase2, Recruiting

SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects

for
Cystic Fibrosis
Location: Cleveland OH, Detroit MI, Columbus OH, Baltimore MD,
Sponsor: Aridis Pharmaceuticals, Inc.

Sex: All

Age: 18 - 49

Code: NCT03669614

Phase1, Phase2, Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for
Non-Small Cell Lung Cancer
Location: Cleveland OH, Detroit MI, London, Pittsburgh PA,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT06767514

Phase3, Recruiting

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for
Proteinuric Kidney Disease
Location: Cleveland OH, Dearborn MI, Pontiac MI, Columbus OH,
Sponsor: Maze Therapeutics

Sex: All

Age: 18 - 68

Code: NCT06830629

Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

for
Asthma
Location: Cleveland OH, Windsor, Detroit MI, Toledo OH, Hamilton,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 11

Code: NCT06023589

Phase3, Recruiting

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A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

for
Advanced or Metastatic Non-small Cell Lung Cancer
Location: Cleveland OH, Baltimore MD, Providence RI, Rochester MN,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06996782

Phase1, Phase2, Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma,
Location: Cleveland OH, Fairfax VA, New York NY, Durham NC,
Sponsor: Plexium, Inc.

Sex: All

Age: 18+

Code: NCT07284186

Phase1, Recruiting

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer (CRC)
Location: Cleveland OH, Mayfield Heights OH, Akron OH, Canton OH,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT07228832

Phase3, Recruiting

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for
Metastatic Clear Cell Renal Cell Carcinoma,
Location: Cleveland OH, London, Monroeville PA, Hamilton,
Sponsor: Arcus Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07011719

Phase3, Recruiting

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

for
Relapsed AL Amyloidosis, Refractory AL Amyloidosis,
Location: Cleveland OH, Detroit MI, Toronto, New York NY,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07081646

Phase1, Phase2, Recruiting

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for
Endometrial Cancer, Malignant Solid Tumour
Location: Cleveland OH, Sylvania OH, Ann Arbor MI, Columbus OH,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07044336

Phase3, Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Cleveland OH, Marion OH, Garden City MI,
Sponsor: AstraZeneca

Sex: All

Age: 40+

Code: NCT07082738

Phase2, Recruiting

Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for
Acute Coronary Syndrome
Location: Cleveland OH, Canton OH, Toledo OH, Dearborn MI,
Sponsor: DalCor Pharmaceuticals

Sex: All

Age: 45+

Code: NCT05918861

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for
Polymyositis, Dermatomyositis
Location: Cleveland OH, Sterling Heights MI, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06455449

Phase3, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Cleveland OH, Detroit MI, Hamilton, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase3, Recruiting

Development of CIRC Technologies

for
Cardiovascular Diseases, Heart Failure, Ischemic Heart Disease,
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT05654272

Recruiting

CV Imaging of Metabolic Interventions

for
Bariatric Surgery Candidate, Heart Failure,
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT05650307

Recruiting

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for
Amblyopia
Location: Cleveland OH, Mayfield Heights OH, Poland OH, Erie PA,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 4 - 7

Code: NCT06380517

Phase3, Recruiting

Corneal Elastography and Patient Specific Modeling

for
Cornea; Ectasia, Refractive Errors, Keratoconus
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 16 - 70+

Code: NCT03030755

Recruiting

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for
Neurotrophic Keratopathy
Location: Cleveland OH, Pittsburgh PA, Carmel IN, Chicago IL,
Sponsor: ReGenTree, LLC

Sex: All

Age: 18+

Code: NCT05555589

Phase3, Recruiting