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Paid Clinical Trials Dayton

Discover 1,187 paid clinical trials in Dayton, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Cincinnati OH, Columbus OH, Fort Wayne IN,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06824467

Phase 3, Recruiting

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

for
Hematological Malignancy, Solid Tumor Malignancy
Location: Cincinnati OH, Charlotte NC, Baltimore MD, Seattle WA
Sponsor: Century Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05768269

Recruiting

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for
Non-small Cell Lung Cancer
Location: Cincinnati OH, Edgewood KY, Lexington KY, Royal Oak MI,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06561386

Phase 3, Recruiting

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for
Stroke, Stroke, Acute, Stroke, Ischemic
Location: Cincinnati OH, Columbus OH, Louisville KY, Cleveland OH,
Sponsor: University of Cincinnati

Sex: All

Age: 18+

Code: NCT05911568

Recruiting

Registry Study for Radiation Therapy Outcomes

for
Neoplasms
Location: Cincinnati OH, Flint MI, Warrenville IL, Knoxville TN,
Sponsor: Proton Collaborative Group

Sex: All

Age: 0+

Code: NCT01255748

Recruiting

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This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.

for
Peripheral Nerve Injury Upper Limb,
Location: Cincinnati OH, Columbus OH, Louisville KY, Cleveland OH,
Sponsor: Neuraptive Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT06616025

Phase 3, Recruiting

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for
Superficial Bladder Cancer,
Location: Cincinnati OH, Gahanna OH, Greenwood IN,
Sponsor: enGene, Inc.

Sex: All

Age: 18+

Code: NCT04752722

Phase 1, Phase 2, Recruiting

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

for
Chronic Lymphocytic Leukemia (CLL),
Location: Cincinnati OH, Cleveland OH, Chicago IL, Milwaukee WI,
Sponsor: Nurix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05131022

Phase 1, Recruiting

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

for
Breast Cancer, TNBC - Triple-Negative Breast Cancer,
Location: Cincinnati OH, Goshen IN, Ann Arbor MI, Nashville TN,
Sponsor: Tempus AI

Sex: All

Age: 18 - 70+

Code: NCT07211178

Recruiting

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

for
Major Depressive Disorder
Location: Cincinnati OH, Columbus OH, Avon Lake OH, O'Fallon MO,
Sponsor: Intra-Cellular Therapies, Inc.

Sex: All

Age: 18 - 65

Code: NCT05850689

Phase 3, Recruiting

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for
Melanoma (Skin Cancer),
Location: Cincinnati OH, Detroit MI, Nashville TN, Madison WI,
Sponsor: Aminex Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07287917

Phase 1, Phase 2, Recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

for
Pulmonary Arterial Hypertension
Location: Cincinnati OH, Louisville KY, Ann Arbor MI,
Sponsor: Gossamer Bio USA, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06274801

Phase 3, Recruiting

Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma

for
Oropharyngeal Squamous Cell Carcinoma,
Location: Cincinnati OH
Sponsor: Sara Medek

Sex: All

Age: 18+

Code: NCT07497607

Phase 2, Recruiting

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

for
Ras-mutated Metastatic Colorectal Cancer, mCRC,
Location: Cincinnati OH, Colombus OH, Indianapolis IN, Canton OH,
Sponsor: Oncolytics Biotech

Sex: All

Age: 18+

Code: NCT07446322

Phase 2, Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for
Ovarian Neoplasms, Ovarian Cancer
Location: Cincinnati OH, Indianapolis IN, Fort Wayne IN,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07318558

Phase 3, Recruiting

Oral 5 Strain Probiotic for GI Toxicity Mitigation During Pelvic Radiation

for
Radiation Injuries
Location: Cincinnati OH
Sponsor: University of Cincinnati

Sex: All

Age: 18+

Code: NCT07231588

Early Phase 1, Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

for
Myasthenia Gravis, MG, gMG, Generalized Myasthenia Gravis,
Location: Cincinnati OH, Columbus OH, Detroit MI, Chattanooga TN,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07294170

Recruiting

Promoting Immunotherapy Efficacy With Low-Dose Liver RT

for
Low-Dose Liver Radiation (LD-LRT), Non Small Cell Lung Cancer,
Location: Cincinnati OH
Sponsor: Jordan Kharofa

Sex: All

Age: 18+

Code: NCT07225036

Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

for
AChR-Ab Seropositive Generalized Myasthenia Gravis,
Location: Cincinnati OH, Columbus OH, Detroit MI, Chattanooga TN,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07284420

Phase 2, Recruiting

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

for
Endometrial Cancer, Recurrent or Progressive Endometrial Cancer
Location: Cincinnati OH, Grand Rapids MI, Evanston IL,
Sponsor: Genmab

Sex: Female

Age: 18+

Code: NCT07166094

Phase 3, Recruiting