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Paid Clinical Trials Dayton

Discover 1,187 paid clinical trials in Dayton, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

for
Nodular Lymphocyte Predominant B-Cell Lymphoma,
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05886036

Phase 2, Recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

for
Melanoma Stage IV, Solid Tumor
Location: Cincinnati OH, Nashville TN, Richmond VA, New York NY,
Sponsor: Georgiamune Inc

Sex: All

Age: 18+

Code: NCT06425926

Phase 1, Phase 2, Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for
Metastatic Colorectal Carcinoma,
Location: Cincinnati OH, West Chester OH, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05803382

Phase 1, Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for
Non-small Cell Lung Cancer
Location: Cincinnati OH, Skokie IL, Hamilton, Madison WI, Toronto,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06345729

Phase 3, Recruiting

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

for
Locally Recurrent Skin Squamous Cell Carcinoma,
Location: Cincinnati OH, West Chester OH, Avon OH, Ann Arbor MI,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07042295

Phase 2, Recruiting

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Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase 3, Recruiting

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18 - 39

Code: NCT03150693

Phase 3, Recruiting

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

for
Colorectal Cancer, Gastric Adenocarcinoma,
Location: Cincinnati OH, Boston MA, Tampa FL, Salt Lake City UT,
Sponsor: Dispatch Biotherapeutics

Sex: All

Age: 18+

Code: NCT07544589

Phase 1, Recruiting

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for
Recurrent Glioblastoma, IDH-Wildtype,
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05432804

Phase 1, Phase 2, Recruiting

A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

for
Schizophrenia, Autism-Related Irritability
Location: Cincinnati OH, Chicago IL, Lawrenceville GA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 5 - 17

Code: NCT07424404

Phase 3, Recruiting

A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for
ALK-positive NSCLC, ALK-Positive Lung Cancer,
Location: Cincinnati OH, Maumee OH, Pittsburgh PA, Nashville TN,
Sponsor: TRIANA Biomedicines, Inc.

Sex: All

Age: 18+

Code: NCT07491497

Phase 1, Phase 2, Recruiting

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03739814

Phase 2, Recruiting

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

for
Cervical Carcinoma, Human Papillomavirus Infection
Location: Cincinnati OH, Morgantown WV, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 25+

Code: NCT07281430

Recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

for
Head and Neck Squamous Cell Carcinoma,
Location: Cincinnati OH, West Chester OH, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06980038

Phase 2, Recruiting

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07061964

Phase 2, Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06532279

Phase 2, Recruiting

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements,
Location: Cincinnati OH, West Chester OH, Columbus OH, Canton OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06649812

Phase 2, Recruiting

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for
Metastatic Salivary Gland Carcinoma,
Location: Cincinnati OH, West Chester OH, Columbus OH,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05408845

Phase 2, Recruiting

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for
Cardiotoxicity, HER2/Neu Positive,
Location: Cincinnati OH, West Chester OH, Indianapolis IN,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT03418961

Phase 3, Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Cincinnati OH, West Chester OH, Chicago IL, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05172245

Phase 1, Recruiting