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Paid Clinical Trials Toronto

Discover 2,121 paid clinical trials in Toronto, Ontario. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for
Myelodysplastic Syndromes, Acute Myeloid Leukemia,
Location: Toronto, Buffalo NY, Columbus OH, Hackensack NJ,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT04256317

Phase 2, Phase 3, Recruiting

Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)

for
Metastatic Prostate Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18 - 70+

Code: NCT05404139

Phase 2, Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Advanced Metastatic Castration-resistant Prostate Cancer,
Location: Toronto, Hamilton, Montreal, Sherbrooke, Vancouver
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06217822

Phase 1, Recruiting

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

for
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers,
Location: Toronto, Hamilton, Ottawa, Montreal, Edmonton
Sponsor: Bold Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04421820

Phase 1, Phase 2, Recruiting

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

for
B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma,
Location: Toronto, Buffalo NY, Detroit MI, New York NY,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT05006716

Phase 1, Phase 2, Recruiting

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R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma

for
Lymphadenopathy Retroperitoneal, Stage II Testicular Seminoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT05345158

Recruiting

PRostate Evaluation for Clinically Important Disease: MRI vs Standard Evaluation Procedures

for
Prostate Cancer
Location: Toronto, London, Montreal
Sponsor: Canadian Urology Research Consortium

Sex: Male

Age: 18+

Code: NCT02936258

Recruiting

A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)

for
Breast Neoplasm Female, Radiotherapy, Cosmetic Outcome
Location: Toronto, Newmarket, Hamilton, Barrie, London, Windsor,
Sponsor: Ontario Clinical Oncology Group (OCOG)

Sex: Female

Age: 50 - 70+

Code: NCT05417516

Phase 3, Recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Toronto, London, Cleveland OH, Detroit MI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase 3, Recruiting

Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma

for
Cutaneous Melanoma, Melanoma Stage IV, Mucosal Melanoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06319196

Phase 2, Recruiting

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for
Triple-Negative Breast Cancer
Location: Toronto, Hamilton, Kingston, Detroit MI, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06393374

Phase 3, Recruiting

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

for
Multiple Myeloma
Location: Toronto, Basking Ridge NJ, Montvale NJ, Harrison NY,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT05623020

Phase 3, Recruiting

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Toronto, Detroit MI, Ottawa, Columbus OH, Baltimore MD,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05384626

Phase 1, Phase 2, Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for
Colorectal Neoplasms
Location: Toronto, Williamsville NY, Mayfield Heights OH,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06662786

Phase 3, Recruiting

HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers

for
Squamous Cell Carcinoma of Head and Neck
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06487403

Recruiting

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Toronto, Mississauga, Greater Sudbury, Pittsburgh PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06824467

Phase 3, Recruiting

Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era

for
Prostate Cancer Recurrent, Prostate Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT06508567

Recruiting

Circulating Tumor DNA in Soft Tissue Sarcoma

for
Soft Tissue Sarcoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03818412

Recruiting

Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy

for
Myelodysplastic Syndrome, Acute Myeloid Leukemia
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 0+

Code: NCT06510868

Recruiting

Red Blood Cell Transfusion Thresholds and QOL in MDS

for
Myelodysplastic Syndromes (MDS), Quality of Life,
Location: Toronto, Hamilton
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT02099669

Recruiting