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Paid Clinical Trials Toronto

Discover 2,121 paid clinical trials in Toronto, Ontario. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Lattice Radiation Therapy Versus Conventional Radiation Therapy for the Palliation of Large Tumors

for
Histopathologically or Cytologically Confirmed Solid Tumor Who Require Palliation Radiation Therapy to a Lesion ≥5cm,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 70+

Code: NCT07444775

Phase 3, Recruiting

Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response

for
Prostate Adenocarcinoma, Iliac Nodal Disease,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT06831032

Recruiting

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction

for
Liver Metastases
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06362395

Phase 3, Recruiting

AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for
Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR),
Location: Toronto, Indianapolis IN, Zion IL, Westbrook ME,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07403721

Phase 1, Recruiting

Stereotactic Ablative Radiotherapy (XRT) and Immunotherapy for Oligometastatic Extracranial Melanoma

for
Melanoma Metastatic
Location: Toronto
Sponsor: Melanoma Institute Australia

Sex: All

Age: 18+

Code: NCT06767306

Phase 2, Recruiting

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Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer

for
Advanced Prostate Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT06335914

Recruiting

Actinium Therapy for Late-stage Aggressive Sarcomas

for
Advanced Soft Tissue Sarcoma
Location: Toronto, Cleveland OH, New York NY, Rochester MN,
Sponsor: Ratio Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07156565

Phase 1, Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma,
Location: Toronto, Pittsburgh PA, New York NY, Lake Success NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07221149

Phase 2, Phase 3, Recruiting

Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma

for
Retroperitoneal Liposarcoma
Location: Toronto, Columbus OH, Atlanta GA, Houston TX
Sponsor: Australia and New Zealand Sarcoma Association

Sex: All

Age: 18+

Code: NCT07377747

Recruiting

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

for
Urothelial Cancer
Location: Toronto, Mayfield Heights OH, Cleveland OH, Detroit MI,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07106762

Phase 2, Phase 3, Recruiting

Study to Assess the Safety and Effects of Porphysome Nanoparticles for Imaging in Gynaecological Cancers

for
Gynecological Cancers
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Female

Age: 18+

Code: NCT06977126

Phase 1, Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

for
Advanced Solid Malignancies, Non-small Cell Lung Cancer (NSCLC),
Location: Toronto, Baltimore MD, Fairfax VA, San Antonio TX,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07223047

Phase 1, Phase 2, Recruiting

Feasibility of a Cognitive Stepped Care Program for Adults With Brain Metastases

for
Brain Metastases, Brain Metastasis
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07355348

Recruiting

Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer

for
Squamous Cell Cancer of Head and Neck (SCCHN)
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07348887

Recruiting

Plan Development for Giving Teclistamab in the Outpatient Setting

for
Multiple Myeloma, Relapsed Cancer, Refractory Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06251076

Recruiting

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

for
Colorectal Cancer
Location: Toronto, Ottawa, Montreal, Columbus OH, Philadelphia PA,
Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT06948448

Phase 2, Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

for
Cervical Cancer
Location: Toronto, London, Montreal, Columbus OH, Willow Grove PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07216703

Phase 3, Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for
Non-Small Cell Lung Cancer
Location: Toronto, Rochester NY, Cleveland OH, Pittsburgh PA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07100080

Phase 2, Phase 3, Recruiting

Feasibility of CALM in Patients With Ovarian Cancer

for
Patient Satisfaction, Ovarian Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Female

Age: 18+

Code: NCT06459271

Recruiting

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for
Castration-Resistant Prostatic Cancer, Metastasis
Location: Toronto, Pittsburgh PA, Ann Arbor MI, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06863272

Phase 1, Phase 2, Recruiting