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Paid Clinical Trials Pennsylvania

Discover 3,064 paid clinical trials in Pennsylvania. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for
Acute Myeloid Leukemia
Location: Hershey PA, Cincinnati OH, Madison WI, Memphis TN,
Sponsor: Norman J. Lacayo

Sex: All

Age: 0 - 21

Code: NCT05101551

Phase1, Recruiting
Active & Responsive

A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

for
Rheumatoid Arthritis (RA)
Location: Duncansville PA, Cutler Bay FL, Miami FL
Sponsor: SynAct Pharma Aps

Sex: All

Age: 18+

Code: NCT06671054

Phase2, Recruiting
Active & Responsive

Pediatric Post-Approval Registry

for
Obstructive Sleep Apnea
Location: Philadelphia PA, Norfolk VA, Durham NC, Sewickley PA,
Sponsor: Inspire Medical Systems, Inc.

Sex: All

Age: 18 - 21

Code: NCT04457154

Recruiting
Active & Responsive

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

for
Carcinoma, Non-Small-Cell Lung
Location: Lebanon NH, Philadelphia PA, Columbus OH, Houston TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT04165798

Recruiting
Active & Responsive

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

for
Colorectal Cancer
Location: York PA, Bethesda MD, Goldsboro NC, Canton OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05234177

Recruiting

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Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Boston MA, New Haven CT, New York NY, Montreal,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase2, Phase3, Recruiting
Active & Responsive

Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

for
Pancreatic Adenocarcinoma Metastatic
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06747845

Phase2, Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: Halifax, Boston MA, New York NY, Philadelphia PA,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase3, Recruiting
Active & Responsive

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

for
Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia
Location: Hershey PA, Coral Gables FL, Tampa FL, Ann Arbor MI,
Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois

Sex: All

Age: 0 - 70+

Code: NCT05500807

Phase1, Recruiting
Active & Responsive

Evaluation of Hypoxia in Primary Melanoma

for
Melanoma
Location: Pittsburgh PA
Sponsor: Yana Najjar

Sex: All

Age: 18+

Code: NCT06831071

Recruiting
Active & Responsive

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

for
Cervical Cancer, Uterine Cancer, Endometrial Cancer
Location: Voorhees Township NJ, Philadelphia PA, Lancaster PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female

Age: 18+

Code: NCT05758688

Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for
Psoriatic Arthritis, Spondyloarthritis, Axial
Location: Quebec, Philadelphia PA, Ottawa, Cleveland OH,
Sponsor: CARE ARTHRITIS LTD.

Sex: All

Age: 18+

Code: NCT06454188

Recruiting
Active & Responsive

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for
Chronic Granulomatous Disease (CGD)
Location: Augusta ME, Boston MA, Providence RI, Concord NH,
Sponsor: Ensoma

Sex: All

Age: 0+

Code: NCT06605378

Recruiting
Active & Responsive

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for
Scoliosis Idiopathic
Location: New York NY, Philadelphia PA, Washington D.C. DC,
Sponsor: Pediatric Spine Foundation

Sex: All

Age: 0 - 18

Code: NCT04914507

Recruiting
Active & Responsive

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for
Extensive Stage-small Cell Lung Cancer
Location: Lebanon NH, Mineola NY, New York NY, Hackensack NJ,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06362252

Phase1, Phase2, Recruiting
Active & Responsive

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for
Prostate Cancer, Prostatic Neoplasms
Location: Boston MA, New Haven CT, West Haven CT, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Male

Age: 18+

Code: NCT06925737

Phase3, Recruiting
Active & Responsive

A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

for
Pressure Ulcer, Stage IV, Osteomyelitis
Location: Mineola NY, Newark NJ, Pittsburgh PA, Detroit MI,
Sponsor: Biocomposites Ltd

Sex: All

Age: 18+

Code: NCT06283979

Phase2, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Pennington NJ, Philadelphia PA, Newark DE, Baltimore MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting
Active & Responsive

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

for
Non-small Cell Lung Cancer, NSCLC
Location: Hackensack NJ, Trois-Rivieres, Pennington NJ, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06422143

Phase3, Recruiting
Active & Responsive

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

for
PIK3CA-Related Overgrowth Spectrum (PROS),
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 2+

Code: NCT06789913

Phase2, Recruiting

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