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Paid Clinical Trials Philadelphia

Discover 2,133 paid clinical trials in Philadelphia, Pennsylvania. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

for
Muscular Atrophy, Spinal
Location: Philadelphia PA, Grand Rapids MI, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 2

Code: NCT05861999

Recruiting
FeaturedActive & Responsive

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

for
Solid Tumor
Location: Philadelphia PA, The Bronx NY, New Haven CT, Boston MA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT06619587

Phase1, Recruiting
FeaturedActive & Responsive

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for
Geographic Atrophy
Location: Philadelphia PA, Baltimore MD, Lynchburg VA, Durham NC,
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT05626114

Phase2, Recruiting
Featured

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for
Huntington Disease
Location: Philadelphia PA, Pittsburgh PA, Boston MA, Columbus OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 25 - 65

Code: NCT06826612

Phase1, Phase2, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Philadelphia PA, Moorestown NJ, New Brunswick NJ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase3, Recruiting

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Featured

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

for
Muscular Atrophy, Spinal
Location: Philadelphia PA, New York NY, Grand Rapids MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 2

Code: NCT05861986

Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Philadelphia PA, New Brunswick NJ, Hershey PA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

for
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer,
Location: Philadelphia PA, Bensalem PA, East Brunswick NJ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06065748

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Philadelphia PA, Boston MA, Charlotte NC, Germantown TN,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT04802759

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

for
Diabetic Macular Edema
Location: Philadelphia PA, Baltimore MD, Lynchburg VA, Erie PA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07425522

Phase1, Recruiting

Philadelphia boasts a strong healthcare network and prominent medical research centers, making it a pivotal location for a diverse range of clinical trials. Renowned institutions such as the University of Pennsylvania, Thomas Jefferson University, and Temple University lead the way in innovative research. These centers are known for their cutting-edge studies across various fields, including oncology, cardiology, neurology, and infectious diseases.

The city’s rich tapestry of clinical research is supported by its diverse population, while the collaborative research environment in Philadelphia also fosters groundbreaking discoveries that can transform patient care and improve health outcomes on a broader scale.

Why choose Philadelphia for clinical trials?

Common conditions studied in Philadelphia

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