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Novel Digital Application for Patients With Acute Leukemia

for
Relapsed Adult Acute Myeloid Leukemia,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT06472128

Recruiting

A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

for
AML, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia,
Location: Fairfax VA, Durham NC, Tyler TX, Houston TX, Dallas TX,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT04358393

Phase1, Phase2, Recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Halifax, Portland ME, Scarborough ME, South Portland ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554393

Phase2, Recruiting

Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/Refractory AML

for
Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)
Location: Houston TX
Sponsor: Hemogenyx Pharmaceuticals LLC

Sex: All

Age: 12+

Code: NCT06786533

Phase1, Recruiting

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

for
Acute Bilineal Leukemia, Acute Biphenotypic Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03683433

Phase2, Recruiting

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Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

for
Acute Myeloid Leukemia
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT03921047

Recruiting

Acute Myeloid Leukemia and Markers of Leukemia Stem Cells (CLL1 and CD45RA)

for
Acute Myeloid Leukemia
Location: Stony Brook NY
Sponsor: Suhu Liu

Sex: All

Age: 18+

Code: NCT06297551

Recruiting

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

for
Acute Myeloid Leukemia (AML)
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06811233

Phase2, Recruiting

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

for
Myeloid Malignancy, Acute Myeloid Leukemia,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT06594445

Phase1, Recruiting

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: New York NY, Atlanta GA
Sponsor: Meryx, Inc.

Sex: All

Age: 12+

Code: NCT04872478

Phase1, Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
AML, AML With Mutated NPM1, Hematologic Malignancy, KMT2Ar,
Location: Boston MA, New Haven CT, Stony Brook NY,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06001788

Phase1, Recruiting

Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 50+

Code: NCT03586609

Phase2, Recruiting

CIML NK Cells With Venetoclax for AML

for
Acute Myeloid Leukemia, Acute Myeloid Leukemia Recurrent,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06152809

Phase1, Recruiting

Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

for
Recurrent Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03629171

Phase2, Recruiting

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

for
Acute Myeloid Leukemia, in Relapse,
Location: Winston-Salem NC, Charlotte NC, Houston TX
Sponsor: ARCE Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06680752

Phase1, Phase2, Recruiting

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

for
Adult Acute Myeloid Leukemia
Location: Baltimore MD, Rochester NY, Tampa FL, Cleveland OH,
Sponsor: Priothera SAS

Sex: All

Age: 18 - 70+

Code: NCT05429632

Phase3, Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06317649

Phase2, Recruiting

Personalized NK Cell Therapy in CBT

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 15 - 70+

Code: NCT02727803

Phase2, Recruiting

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

for
Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS,
Location: Baltimore MD, Washington D.C. DC
Sponsor: Catherine Bollard

Sex: All

Age: 0 - 70+

Code: NCT02203903

Phase1, Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Halifax, Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase2, Recruiting