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Canadian Network for Autoimmune Liver Disease

for
Primary Bilary Cirrhosis (PBC), Autoimmune Hepatitis,
Location: Sherbrooke, Montreal, Ottawa, Toronto, London,
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03569826

Recruiting

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

for
Chronic Inflammatory Demyelinating Polyneuropathy,
Location: New York NY, Montreal, Salt Lake City UT, Seattle WA,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18 - 70+

Code: NCT07304154

Phase1, Recruiting

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

for
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
Location: Pittsburgh PA, Columbus OH, Cincinnati OH,
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT05750498

Recruiting

Autoimmune Blistering Diseases Study

for
Pemphigus Vulgaris, Pemphigus Foliaceus, Bullous Pemphigoid
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT02753777

Recruiting

Preoperative Corticosteroids in Autoimmune Thyroid Disease

for
Graves Disease, Hashimoto Disease
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT05435547

Recruiting

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Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease

for
Autoimmune Inner Ear Disease, Meniere's Disease
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: All

Age: 18 - 70+

Code: NCT03587701

Phase2, Recruiting

Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets

for
Meniere's Disease, Enlarged Vestibular Aqueduct Syndrome,
Location: Bethesda MD
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)

Sex: All

Age: 18 - 70+

Code: NCT04806282

Recruiting
New

Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) Population

for
GVHD
Location: Ann Arbor MI
Sponsor: Sung Won Choi

Sex: All

Age: 1 - 26

Code: NCT06995521

Phase2, Recruiting

Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

for
Graft Vs Host Disease, Graft-versus-host-disease,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06008808

Phase1, Recruiting

Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Disease

for
Intestinal Graft Versus Host Disease
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT05067595

Phase1, Recruiting

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

for
Chronic Graft vs. Host Disease
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 70+

Code: NCT00092235

Recruiting

PTCY Plus uhCG/EGF for Graft Versus Host Disease Prophylaxis

for
Graft Versus Host Disease
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18 - 70

Code: NCT04886726

Phase1, Recruiting

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for
Graft-versus-host Disease (GVHD)
Location: Boston MA, New York NY, Philadelphia PA, Richmond VA,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT06615050

Phase3, Recruiting

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

for
Chronic Graft-versus-host Disease (cGVHD)
Location: Philadelphia PA, Richmond VA, Charlottesville VA,
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06660355

Phase2, Recruiting

Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

for
Graft vs Host Disease
Location: Bethesda MD, Miami FL
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05531786

Phase1, Phase2, Recruiting

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for
Chronic Graft-versus-host-disease
Location: Halifax, Boston MA, Stony Brook NY, Hackensack NJ,
Sponsor: Incyte Corporation

Sex: All

Age: 12+

Code: NCT06585774

Phase3, Recruiting

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

for
Graft Vs Host Disease, Acute-graft-versus-host Disease,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05236062

Recruiting

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

for
Graft Vs Host Disease, Vulvovaginal Signs and Symptoms
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: Female

Age: 18 - 70

Code: NCT06649201

Recruiting

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

for
Acute Graft Versus Host Disease,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05443425

Phase1, Recruiting

A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

for
Graft-Versus-Host Disease, GVHD, Undefined
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 4+

Code: NCT05675930

Phase2, Recruiting