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High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease

for
Exacerbation Copd, Acute Respiratory Distress,
Location: Toronto
Sponsor: Unity Health Toronto

Sex: All

Age: 40+

Code: NCT03033251

Recruiting

The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)

for
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease,
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 40 - 70+

Code: NCT05237505

Phase2, Recruiting

Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial

for
Chronic Obstructive Pulmonary Disease
Location: Saskatoon, Edmonton, Wetaskiwin, Lethbridge, Calgary,
Sponsor: University of British Columbia

Sex: All

Age: 45+

Code: NCT00120978

Recruiting

Pulmonary Rehabilitation for Rural Patients With COPD

for
Chronic Obstructive Pulmonary Disease (COPD
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 40+

Code: NCT06847061

Recruiting

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

for
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea,
Location: Chicago IL, Minneapolis MN, Spokane WA, Boise ID,
Sponsor: Seattle Institute for Biomedical and Clinical Research

Sex: All

Age: 18+

Code: NCT06390345

Recruiting

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Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

for
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension,
Location: Boston MA, Providence RI, Decatur GA, Omaha NE,
Sponsor: VA Office of Research and Development

Sex: All

Age: 35 - 70+

Code: NCT05937854

Phase2, Recruiting

Improving Participation in Pulmonary Rehabilitation Through Peer Support and Storytelling

for
Chronic Obstructive Pulmonary Disease
Location: Springfield MA
Sponsor: Baystate Medical Center

Sex: All

Age: 40+

Code: NCT05399056

Recruiting

Biological Effects of Quercetin in COPD

for
Chronic Obstructive Pulmonary Disease
Location: Philadelphia PA
Sponsor: Temple University

Sex: All

Age: 40 - 70+

Code: NCT03989271

Phase1, Phase2, Recruiting

Move With Air: Exercise Training Study

for
Chronic Obstructive Pulmonary Disease,
Location: Montreal
Sponsor: McGill University

Sex: All

Age: 40+

Code: NCT05646407

Recruiting

PRagmatic EVAluation of a Quality Improvement Program for People Living With Modifiable High-risk COPD.

for
Chronic Obstructive Pulmonary Disease
Location: New York NY, Cleveland OH, Denver CO
Sponsor: Observational and Pragmatic Research Institute

Sex: All

Age: 18+

Code: NCT05306743

Recruiting

Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

for
Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
Location: Boston MA
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 40+

Code: NCT05934565

Recruiting
New

A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-1)

for
Pulmonary Disease, Chronic Obstructive
Location: Doral FL, Lake Charles LA
Sponsor: GlaxoSmithKline

Sex: All

Age: 40 - 70+

Code: NCT07780669

Phase3, Recruiting

Viral Mucosal Reprogramming

for
Asthma, Allergic Rhinitis, Cat Allergy, Healthy
Location: Galveston TX
Sponsor: The University of Texas Medical Branch, Galveston

Sex: All

Age: 18 - 60

Code: NCT05331170

Phase2, Recruiting

Trial to Determine Effective Aspirin Dose in COPD

for
Pulmonary Disease, Chronic Obstructive
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 40 - 70+

Code: NCT05265299

Phase3, Recruiting

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

for
Pulmonary Disease, Chronic Obstructive
Location: Bangor ME, West Chester PA, Kingston, Miami FL,
Sponsor: GlaxoSmithKline

Sex: All

Age: 40 - 70+

Code: NCT07177339

Phase3, Recruiting

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)

for
Pulmonary Disease, Chronic Obstructive
Location: Miami FL, Loxahatchee Groves FL, Rock Hill SC,
Sponsor: GlaxoSmithKline

Sex: All

Age: 40 - 70+

Code: NCT06959095

Phase3, Recruiting

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for
Pulmonary Disease, Chronic Obstructive
Location: Bangor ME, Mount Kisco NY, New Windsor NY,
Sponsor: GlaxoSmithKline

Sex: All

Age: 40 - 70+

Code: NCT06961214

Phase3, Recruiting

REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis

for
Cancer-Associated Thrombosis (CAT)
Location: North Miami Beach FL, Hialeah FL, El Paso TX
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07410117

Phase3, Recruiting

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for
Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors
Location: Boston MA, Providence RI, Norwalk CT, New York NY,
Sponsor: Fore Biotherapeutics

Sex: All

Age: 8+

Code: NCT05503797

Phase2, Recruiting

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

for
Nonsmall Cell Lung Cancer, Performance Status
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT04253964

Phase2, Recruiting