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Active & Responsive

tDCS: Sleep to Mood in Depression (S2M-D)

for
Major Depressive Disorder, MDD, Depression,
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 65

Code: NCT07572526

Recruiting
Active & Responsive

Exercise-priming of CBT for Depression: the CBT+ Trial

for
Major Depressive Disorder
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18 - 65

Code: NCT07221929

Recruiting
Active & Responsive

A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

for
Depression, Anxiety, Major Depressive Disorder
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 21 - 65

Code: NCT06820723

Phase2, Recruiting
Active & Responsive

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

for
Mood Disorders, Anxiety Disorders, Healthy Volunteers,
Location: Bethesda MD
Sponsor: National Institute of Mental Health (NIMH)

Sex: All

Age: 3 - 70+

Code: NCT00024635

Recruiting
Active & Responsive

Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

for
ADHD, Depression Disorders, Mood Disorders,
Location: Philadelphia PA
Sponsor: Gaize

Sex: All

Age: 18 - 65

Code: NCT07389473

Recruiting

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Active & Responsive

rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression

for
Depression, Treatment Resistant
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 70

Code: NCT06511544

Recruiting
Active & Responsive

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for
Treatment Resistant Depression
Location: Watertown MA, Springfield MA, Eatontown NJ, New York NY,
Sponsor: atai Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06524830

Phase2, Recruiting
Active & Responsive

Psilocybin-Assisted Therapy for Intergenerational Trauma

for
Psychological Stress, Depression, Anxiety
Location: New York NY
Sponsor: Rachel Yehuda

Sex: All

Age: 18+

Code: NCT06899165

Phase2, Recruiting
Active & Responsive

Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors

for
Suicidal Behaviors, Suicide Ideation, Depression/Anxiety
Location: Colorado Springs CO
Sponsor: University of Memphis

Sex: All

Age: 18+

Code: NCT06318962

Recruiting
Active & Responsive

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

for
Depression, Alcoholism, Drug Abuse
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 64

Code: NCT02604277

Recruiting
Active & Responsive

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

for
Major Depressive Disorder (MDD), Depression in Adults,
Location: New Haven CT, Toms River NJ, Philadelphia PA,
Sponsor: Cybin IRL Limited

Sex: All

Age: 18 - 70+

Code: NCT06793397

Phase3, Recruiting
Active & Responsive

Cognition and Behavior With Sham Accelerated TMS

for
Depression
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 15 - 25

Code: NCT07397858

Recruiting
Active & Responsive

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for
Major Depressive Disorder
Location: Worcester MA, New York NY, Philadelphia PA, Towson MD,
Sponsor: Syndeio Biosciences, Inc

Sex: All

Age: 18 - 64

Code: NCT07115329

Phase2, Recruiting
Active & Responsive

MicroRNA Correlates of Childhood Maltreatment and Suicidality

for
Major Depressive Disorder, Suicidal Ideation
Location: Huntsville AL, Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 60

Code: NCT04923685

Recruiting
Active & Responsive

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

for
Bipolar II Disorder, Depression, Bipolar, Suicidality
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 25 - 70

Code: NCT06706232

Phase2, Recruiting
Active & Responsive

Concurrent TMS-fMRI

for
Healthy Control, Depression
Location: Iowa City IA
Sponsor: Jing Jiang

Sex: All

Age: 18 - 65

Code: NCT06633913

Recruiting
Active & Responsive

Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

for
Wellness, Quality of Life, Anxiety, Depression
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18 - 65

Code: NCT05810259

Recruiting
Active & Responsive

Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression

for
Depression, Anxiety, Fear, Depression, Anxiety and Fear,
Location: Tulsa OK
Sponsor: Laureate Institute for Brain Research, Inc.

Sex: All

Age: 18 - 65

Code: NCT06004115

Recruiting
Active & Responsive

Treating Major Depression With Yoga Mono-therapy

for
Depression Mild, Depression Moderate
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06091527

Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Watertown MA, Worcester MA, Brooklyn NY, Cary NC,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting