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Active & Responsive

A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes

for
Diabetes Mellitus, Type 1, Impaired Hypoglycemic Awareness,
Location: Boston MA, Montreal, Philadelphia PA, Richmond VA,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 65

Code: NCT04786262

Phase3, Recruiting
Active & Responsive

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

for
Diabetic Nephropathies, Kidney Failure, Chronic,
Location: Boston MA, The Bronx NY, Montreal, Syracuse NY, Toronto,
Sponsor: Alessandro Doria

Sex: All

Age: 18 - 70+

Code: NCT06217302

Phase3, Recruiting
Active & Responsive

Healthy Outcomes for Muscle with Exercise in T1D

for
Diabetes Mellitus, Type 1
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 18 - 65

Code: NCT05740514

Recruiting
Active & Responsive

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

for
Diabetes Mellitus, Type 1, Hypoglycemia,
Location: Chicago IL
Sponsor: Otsuka Pharmaceutical Factory, Inc.

Sex: All

Age: 35 - 70

Code: NCT06575426

Phase1, Phase2, Recruiting
Active & Responsive

Fasted Exercise Training in Type 1 Diabetes (FED-T1D)

for
Diabetes Mellitus, Type 1
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18 - 55

Code: NCT06748963

Recruiting

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Active & Responsive

Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART

for
Diabetes type1, Diabetes Mellitus, Type 1, Diabetes, Autoimmune,
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 30+

Code: NCT06405373

Recruiting
Active & Responsive

Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes

for
Diabetes Mellitus, Type 1, Diabetes Complications
Location: Boston MA, The Bronx NY
Sponsor: Boston Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06236607

Recruiting
Active & Responsive

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

for
Diabetes Mellitus, Type 1
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 5 - 12

Code: NCT05899166

Recruiting
Active & Responsive

Circadian Mechanisms, Glucose, and CV Risks in T1D

for
Type 1 Diabetes (T1D)
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 50

Code: NCT06624046

Recruiting
Active & Responsive

Cholesterol Lowering and Residual Risk in Diabetes, Type 1

for
Type 1 Diabetes
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 70+

Code: NCT05641753

Recruiting
Active & Responsive

T1CARE: A Trial of a Novel Intervention to Address Social Determinants of Health in Young Adults With Type 1 Diabetes

for
Type 1 Diabetes
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18 - 40

Code: NCT07059806

Recruiting
Active & Responsive

Type 1 Diabetes Extension Study

for
Type 1 Diabetes Mellitus, T1DM, T1D
Location: Boston MA, Indianapolis IN, Iowa City IA,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 8 - 35

Code: NCT02734277

Recruiting
Active & Responsive

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

for
Type 1 Diabetes Mellitus,
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18 - 60

Code: NCT06609356

Early_phase1, Recruiting
Active & Responsive

Immune Function and the Progression to T1D

for
Type 1 Diabetes
Location: Gainesville FL, Columbus OH, Houston TX
Sponsor: University of Florida

Sex: All

Age: 0 - 70+

Code: NCT05899439

Recruiting
Active & ResponsiveNew

Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG

for
Type 1 Diabetes Mellitus
Location: New Haven CT, New York NY, Pittsburgh PA,
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 4 - 34

Code: NCT07216391

Phase2, Recruiting
Active & Responsive

Effect of C-peptide on Hypoglycemic Counterregulation

for
Hypoglycemia, Type 1 Diabetes
Location: Cincinnati OH
Sponsor: University of Cincinnati

Sex: All

Age: 18 - 40

Code: NCT06470295

Early_phase1, Recruiting
Active & Responsive

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

for
Type 1 Diabetes, Diabetic Kidney Disease,
Location: Seattle WA
Sponsor: Kalie Tommerdahl

Sex: All

Age: 12 - 25

Code: NCT05065372

Phase1, Recruiting
Active & Responsive

Family Intervention for Black Teens With Type 1 Diabetes

for
Type 1 Diabetes, Family Relations
Location: Washington D.C. DC, Detroit MI, Memphis TN
Sponsor: Wayne State University

Sex: All

Age: 10 - 14

Code: NCT06275412

Recruiting
Active & Responsive

Exercise and the Menstrual Cycle in Type 1 Diabetes

for
Type 1 Diabetes
Location: Edmonton
Sponsor: University of Alberta

Sex: Female

Age: 18 - 50

Code: NCT05188014

Recruiting
Active & Responsive

Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors

for
Diabetes, Type1diabetes, T1D
Location: Montreal
Sponsor: McGill University

Sex: All

Age: 18+

Code: NCT06753994

Phase1, Recruiting