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Active & Responsive

An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)

for
Dilated Cardiomyopathy (DCM),
Location: Montreal, Miami FL, Kansas City MO, Houston TX
Sponsor: Affinia Therapeutics

Sex: All

Age: 18 - 70

Code: NCT07426419

Phase1, Phase2, Recruiting
Active & Responsive

AAVrh10-PCCA Gene Therapy for Propionic Acidemia

for
Propionic Acidemia
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0 - 2

Code: NCT07643844

Phase1, Recruiting
Active & Responsive

Gene Therapy for Alpha 1- Antitrypsin Deficiency

for
Alpha 1-Antitrypsin Deficiency
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18 - 70

Code: NCT06996756

Phase1, Recruiting
Active & Responsive

A Gaucher Disease Gene Therapy Trial With FLT201

for
Gaucher Disease Type 1
Location: New York NY, Montreal, Philadelphia PA, Fairfax VA,
Sponsor: Spur Therapeutics

Sex: All

Age: 18+

Code: NCT07223944

Phase3, Recruiting
Active & Responsive

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

for
Vestibular Schwannoma
Location: Baltimore MD, Nashville TN, Rochester MN, Dallas TX
Sponsor: Akouos, Inc.

Sex: All

Age: 18+

Code: NCT06517888

Phase1, Phase2, Recruiting

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Active & Responsive

Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia

for
Avoidant/Restrictive Food Intake Disorder, Dyspepsia,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05587127

Recruiting
Active & ResponsiveNew

Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, Immunotherapy, Neoadjuvant Therapy
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT06743581

Recruiting
Active & Responsive

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

for
Non-Small Cell Carcinoma of Lung, TNM Stage 4,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT03042221

Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

for
HIV, Depression in Adults, Insulin Resistance,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07226128

Recruiting
Active & Responsive

Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance

for
Obesity, Childhood, Insulin Resistance
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 12 - 18

Code: NCT04578652

Phase3, Recruiting
Active & Responsive

MDMA Therapy in Veterans With PTSD

for
Post Traumatic Stress Disorder
Location: Rockville MD
Sponsor: Sunstone Medical

Sex: All

Age: 18+

Code: NCT07569159

Phase2, Recruiting
Active & Responsive

Healing ALS Registry Observational Study (HAROS)

for
Amyotrophic Lateral Sclerosis (ALS), Motor Neuron Disease (MND),
Location: Park City UT
Sponsor: Healing Advocates Registry and Ministry

Sex: All

Age: 18 - 70+

Code: NCT07233148

Recruiting
Active & Responsive

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06868433

Phase1, Recruiting
Active & Responsive

taVNS for Persistent Symptoms From Lyme Disease

for
Post-Treatment Lyme Disease
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18 - 65

Code: NCT05776251

Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Waterford CT, New Haven CT, Stony Brook NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase2, Recruiting
Active & Responsive

MDMA-Assisted Massed Exposure Therapy for PTSD

for
Post Traumatic Stress Disorder
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 21 - 70

Code: NCT07288151

Phase2, Recruiting
Active & Responsive

Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer

for
Small-cell Lung Cancer
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT04342429

Recruiting
Active & Responsive

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Neptune City NJ, Montreal, Syracuse NY, Ottawa, Toronto,
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18+

Code: NCT02468024

Phase3, Recruiting
Active & Responsive

Telehealth Cognitive Behavioral Therapy for Youth at Risk for Psychosis

for
Clinical High Risk for Psychosis (CHR)
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 14 - 25

Code: NCT05968560

Recruiting