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Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease

for
Sickle Cell Disease
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 1 - 30

Code: NCT03279094

Phase1, Recruiting

Spatial Scene Recognition Memory in Epilepsy Surgery

for
Focal Epilepsy, Temporal Lobe Epilepsy,
Location: Atlanta GA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18 - 55

Code: NCT07580183

Recruiting

Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

for
Relapsed or Refractory Large B-cell Lymphoma
Location: New Haven CT, Quebec, New York NY, Montreal,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18+

Code: NCT07479797

Phase3, Recruiting

A Feasibility Study of Biometric Measurements Via Wearable Smart Watch Technology for Evaluation of Vasomotor Symptoms in Patients Treated With Androgen Deprivation Therapy for Prostate Cancer (Prostate 007)

for
Prostate Cancer, Hot Flashes
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: Male

Age: 18+

Code: NCT07535541

Recruiting

A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

for
Emphysema or COPD, Emphysema, COPD
Location: Boston MA, Chicago IL, San Francisco CA
Sponsor: Pulmair Medical, Inc.

Sex: All

Age: 22+

Code: NCT07119229

Recruiting

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Early DHA/ARA Supplementation in Growth-restricted Very Preterm Infants: A Randomized Clinical Trial

for
Infant Malnutrition,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 0

Code: NCT06207071

Recruiting

Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells

for
T-cell Acute Lymphoblastic Lymphoma, T-non-Hodgkin Lymphoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 70+

Code: NCT07220993

Phase1, Recruiting

Virtual Diabetes Care for Adults With Type 2 Diabetes on Medicaid and Insulin Therapy

for
Type 2 Diabetes
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT06814184

Recruiting

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

for
Treatment-resistant Depression (TRD)
Location: Annapolis MD, Savannah GA, Saint Augustine FL,
Sponsor: Alto Neuroscience

Sex: All

Age: 18 - 70+

Code: NCT07553637

Phase2, Recruiting

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

for
Insulin Resistance, Depression, Depressive Disorder,
Location: Aurora CO, Fort Collins CO
Sponsor: Colorado State University

Sex: Female

Age: 12 - 17

Code: NCT05543083

Recruiting

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

for
Coronary Arterial Disease (CAD)
Location: Jacksonville FL
Sponsor: University of Florida

Sex: All

Age: 18+

Code: NCT07225842

Recruiting

N-803 in Patients With Progressive Synovial Sarcoma and Myxoid/Round Cell Liposarcoma Previously Treated With Adoptive Cellular Therapy

for
Myxoid Liposarcoma, Round Cell Liposarcoma, Synovial Sarcoma
Location: Chicago IL
Sponsor: Seth Pollack

Sex: All

Age: 18 - 70+

Code: NCT07261657

Early_phase1, Recruiting

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for
Anaplastic Large Cell Lymphoma, ALK-Negative,
Location: Millville DE, Lewes DE, Rehoboth Beach DE,
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18 - 70+

Code: NCT06724237

Phase3, Recruiting

Lorlatinib Plus Local Consolidation Therapy In ALK Positive Advanced Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07415005

Phase2, Recruiting

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

for
Bladder Cancer, Non-Muscle Invasive Bladder Cancer (NMIBC),
Location: Iowa City IA
Sponsor: Michael A. O'Donnell

Sex: All

Age: 18 - 70+

Code: NCT07322263

Phase2, Recruiting

A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: New York NY, Fairfax VA, Toronto
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07227025

Phase1, Phase2, Recruiting

Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07365306

Phase2, Recruiting

Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes

for
Gestational Diabetes Mellitus (GDM), Diabetes Type 2,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT07176793

Recruiting

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

for
Total Knee Replacement Surgery, Post-operative Pain
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18 - 70+

Code: NCT07548385

Phase3, Recruiting

Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

for
Non Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer,
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05681780

Phase1, Recruiting