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Promoting Immunotherapy Efficacy With Low-Dose Liver RT

for
Low-Dose Liver Radiation (LD-LRT), Non Small Cell Lung Cancer,
Location: Cincinnati OH
Sponsor: Jordan Kharofa

Sex: All

Age: 18+

Code: NCT07225036

Recruiting

Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery

for
ACL Injury, Hip Injuries
Location: Cleveland OH
Sponsor: University Hospitals Cleveland Medical Center

Sex: All

Age: 14 - 30

Code: NCT05488054

Recruiting

Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)

for
Clear Cell Renal Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07187778

Phase2, Recruiting

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for
Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell Lymphoma
Location: Baltimore MD, Charlottesville VA, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07003295

Phase2, Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Stony Brook NY, Lake Success NY, Rego Park NY,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06686771

Phase3, Recruiting

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WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT05879250

Phase2, Recruiting

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

for
Pneumothorax, Cardiac Surgery, Lung Ultrasound,
Location: Toronto
Sponsor: Jacobo Moreno Garijo

Sex: All

Age: 18+

Code: NCT07018856

Recruiting

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for
Large B-cell Lymphoma, Lymphoma, B-Cell,
Location: Hackensack NJ, Norfolk VA, Durham NC, Buffalo NY,
Sponsor: Lyell Immunopharma, Inc.

Sex: All

Age: 18+

Code: NCT07188558

Phase3, Recruiting

Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer

for
Squamous Cell Cancer of Head and Neck (SCCHN)
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07348887

Recruiting

Supraglottic Airway for Resuscitation Trial

for
Neonatal Resuscitation, Delivery Room Resuscitation,
Location: Brunswick ME, Portland ME, Boston MA, Philadelphia PA,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0+

Code: NCT07150923

Recruiting

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

for
Orthopedic Trauma Surgery Patients, Postoperative Pain,
Location: Lubbock TX
Sponsor: Texas Tech University Health Sciences Center

Sex: All

Age: 18 - 65

Code: NCT06903819

Recruiting

Cold and Compression Post TKA

for
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery,
Location: New Orleans LA
Sponsor: Ochsner Health System

Sex: All

Age: 50+

Code: NCT07023185

Recruiting

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

for
Squamous Cell Carcinoma of Head and Neck
Location: Boston MA, The Bronx NY, Philadelphia PA,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 18 - 70+

Code: NCT07219212

Phase1, Recruiting

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

for
Wound Healing and Prevention, Oral Inflammation,
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT07095556

Recruiting

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

for
Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal,
Location: Austin TX
Sponsor: Stephanie Grasso

Sex: All

Age: 40+

Code: NCT05741853

Recruiting

Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study

for
Post Operative Pain, Spinal Surgery
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18 - 70+

Code: NCT07222072

Recruiting

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for
Extensive-stage Small-cell Lung Cancer
Location: Burlington MA, White Plains NY, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712355

Phase3, Recruiting

Food and Circadian Timing

for
Diet, High-Fat, Circadian Rhythm
Location: Portland OR
Sponsor: Oregon Health and Science University

Sex: All

Age: 18 - 40

Code: NCT04743271

Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for
Non-Small Cell Lung Cancer
Location: Boston MA, Mineola NY, New York NY, Philadelphia PA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07100080

Phase2, Phase3, Recruiting

Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

for
Renal Cell Carcinoma, Non Small Cell Lung Cancer, Melanoma,
Location: Pittsburgh PA
Sponsor: Diwakar Davar

Sex: All

Age: 18+

Code: NCT07223424

Phase2, Recruiting