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Treating Insomnia in Mild Cognitive Impairment

for
Mild Cognitive Impairment (MCI), Insomnia
Location: Boston MA
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 60+

Code: NCT06687161

Recruiting

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

for
Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS),
Location: Boston MA, New York NY, Chapel Hill NC, Columbus OH,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT06465953

Phase3, Recruiting

Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

for
Peripheral Neuropathies,
Location: Amherst NY, Pittsburgh PA, Galveston TX
Sponsor: RxFunction Inc.

Sex: All

Age: 55+

Code: NCT06959277

Recruiting

Study of CAR-T Therapy in Older Patients

for
Lymphoma, Refractory B-Cell Lymphoma, Lymphoma, B-Cell,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT04300998

Recruiting

Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.

for
Oropharyngeal Squamous Cell Carcinoma,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT07044635

Phase2, Recruiting

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Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas

for
Basal Cell Carcinoma (BCC)
Location: Phoenix AZ
Sponsor: Nathalie Zeitouni

Sex: All

Age: 18+

Code: NCT06623201

Phase1, Recruiting

Adapting Rehabilitation Delivery for Maximum Impact at Home-2 (ReDI-2)

for
Knee Osteoarthritis, Hip Osteoarthritis
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 0+

Code: NCT07055113

Recruiting

A Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS)

for
MDS
Location: The Bronx NY
Sponsor: Treebough Therapies

Sex: All

Age: 18+

Code: NCT07006025

Phase1, Recruiting

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

for
Head and Neck Squamous Cell Carcinoma,
Location: Damariscotta ME, Bath ME, Augusta ME, Brunswick ME,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06992427

Phase3, Recruiting

Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

for
Cutaneous Squamous Cell Carcinoma of the Head and Neck,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06990737

Phase2, Recruiting

G-CSF After Chemo-radiation in Patients With Glioblastoma

for
MGMT-Methylated Glioblastoma, Glioblastoma (GBM),
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06649851

Phase2, Recruiting

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

for
PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy,
Location: El Paso TX, Murray UT, Los Angeles CA
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT07226986

Phase1, Phase2, Recruiting

HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission

for
Breast Cancer, HER2-positive Breast Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07459673

Phase2, Recruiting

Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population

for
Medial Patellofemoral Ligament (MPFL) Reconstruction,
Location: Frisco TX
Sponsor: Texas Scottish Rite Hospital for Children

Sex: All

Age: 13 - 21

Code: NCT06559215

Phase2, Recruiting

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for
Carcinoma, Renal Cell, Advanced Renal Cell Carcinoma,
Location: Boston MA, Newton MA, Commack NY, Uniondale NY,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227415

Phase1, Phase2, Recruiting

NT-I7 (Efineptakin Alfa), a Long-acting Human IL-7, Post-Axicabtagene Ciloleucel or Post-Lisocabtagene Maraleucel in Subjects With Relapsed/Refractory Large B-cell Lymphoma

for
Large B-cell Lymphoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07052305

Phase1, Recruiting

Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)

for
Relapsed / Refractory Osteosarcoma
Location: Boston MA, Los Angeles CA
Sponsor: Lantheus Medical Imaging

Sex: All

Age: 12+

Code: NCT07357519

Phase1, Phase2, Recruiting

Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL

for
B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05702853

Phase1, Phase2, Recruiting

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04892277

Phase1, Recruiting

Dextenza in the Post-op Management of Vitreoretinal Surgeries

for
Vitreoretinal Surgery, Ocular Inflammation, Post-operative Pain,
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT04371445

Recruiting