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Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

for
Breast Cancer Surgery
Location: New Haven CT, Quebec, Montreal, Philadelphia PA,
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Sex: Female

Age: 18 - 70+

Code: NCT06888388

Recruiting

Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

for
Post-Traumatic Stress Disorder
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 7 - 18

Code: NCT06332209

Recruiting

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06660407

Phase2, Recruiting

Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients

for
Small Cell Lung Cancer Extensive Stage
Location: Fairfax VA, Canton OH, Cincinnati OH, Fairfield OH,
Sponsor: Genprex, Inc.

Sex: All

Age: 18+

Code: NCT05703971

Phase1, Phase2, Recruiting

Preoperative Radioimmunotherapy Versus Chemoimmunotherapy in NSCLC

for
Carcinoma, Non-Small-Cell Lung
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT06623656

Phase2, Recruiting

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Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

for
Neoplasm, Colorectal, Cognitive Impairment,
Location: Fort Wayne IN
Sponsor: Joseph McCollom

Sex: All

Age: 18+

Code: NCT05014399

Recruiting

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

for
Langerhans Cell Histiocytosis
Location: Allentown PA, Norfolk VA, Columbus OH, Houston TX,
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 21

Code: NCT02670707

Phase3, Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for
Head and Neck Squamous Cell Carcinoma,
Location: Weston WI, Bremerton WA
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT02734537

Phase2, Recruiting

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for
Embryonal Rhabdomyosarcoma,
Location: Halifax, Scarborough ME, Boston MA, Providence RI,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT05304585

Phase3, Recruiting

Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors

for
Advanced Solid Tumor,
Location: Boston MA, Lebanon NH, Morristown NJ,
Sponsor: Vaxiion Therapeutics

Sex: All

Age: 18+

Code: NCT05901285

Phase1, Recruiting

IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

for
NHL, Multiple Myeloma, Blood Cancer,
Location: Providence RI, Fairfax VA, Winston-Salem NC,
Sponsor: Indapta Therapeutics, INC.

Sex: All

Age: 18+

Code: NCT06119685

Phase1, Phase2, Recruiting

Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation

for
Spatial Neglect After Right Brain Stroke
Location: West Haven CT, Leeds MA, Cleveland OH, Decatur GA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05983185

Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for
Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma,
Location: Saint Johnsbury VT, Lebanon NH, New York NY,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05633615

Phase2, Recruiting

Healthy Recovery After Trauma Study

for
Stress Disorders, Post-Traumatic, Shame, Guilt,
Location: Lexington KY
Sponsor: Christal L Badour

Sex: All

Age: 18+

Code: NCT04585685

Recruiting

Co-administration of CART22-65s and huCART19 for B-ALL

for
B-cell Acute Lymphoblastic Leukemia,
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT05674175

Phase1, Phase2, Recruiting

MDMA for Co-occurring PTSD and OUD After Childbirth

for
Stress Disorders, Post-Traumatic, Opioid Use Disorder
Location: Albuquerque NM
Sponsor: University of New Mexico

Sex: Female

Age: 18+

Code: NCT05219175

Phase2, Recruiting

Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer

for
Merkel Cell Carcinoma
Location: New York NY, Madison WI, Iowa City IA
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT05583708

Phase2, Recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer

for
Breast Cancer, HER2-positive Breast Cancer
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT06441890

Phase2, Recruiting

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for
Gastroesophageal-junction Cancer, Monoclonal Antibody,
Location: Sayre PA, West Palm Beach FL, Pompano Beach FL,
Sponsor: Shanghai Henlius Biotech

Sex: All

Age: 18+

Code: NCT06532006

Phase3, Recruiting

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression

for
Diabetes, Type 1 Diabetes
Location: Boston MA, The Bronx NY
Sponsor: Albert Einstein College of Medicine

Sex: All

Age: 18 - 64

Code: NCT05734313

Recruiting