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Active & Responsive

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

for
Chronic Pain, Acute Pain, Post Operative Pain,
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT05754190

Recruiting
Active & ResponsiveNew

Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis

for
Clinical High Risk for Psychosis (CHR), Psychotic Disorders,
Location: Verdun
Sponsor: Douglas Mental Health University Institute

Sex: All

Age: 18 - 34

Code: NCT07786714

Recruiting
Active & ResponsiveNew

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07619599

Phase1, Recruiting
Active & ResponsiveNew

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

for
Fuchs Endothelial Corneal Dysfunction,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 20 - 70+

Code: NCT07780890

Recruiting
Active & ResponsiveNew

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Stony Brook NY, Wilmington DE, Chadds Ford PA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07441681

Phase3, Recruiting

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Active & Responsive

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

for
Kidney Transplant, Kidney Failure,
Location: Boston MA, New York NY, Philadelphia PA
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 65

Code: NCT06056102

Phase1, Recruiting
Active & Responsive

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

for
Alzheimer Disease, Alzheimer Disease, Early Onset,
Location: Cambridge MA
Sponsor: Massachusetts Institute of Technology

Sex: All

Age: 65 - 70+

Code: NCT05655195

Recruiting
Active & Responsive

ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community

for
Type 2 Diabetes
Location: Conroe TX
Sponsor: Sam Houston State University

Sex: All

Age: 18+

Code: NCT06028503

Recruiting
Active & Responsive

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

for
Non-small Cell Lung Cancer
Location: New York NY, Tampa FL, Elizabethtown KY, Birmingham AL
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06841055

Phase2, Recruiting
Active & Responsive

The Effects of Bariatric Surgeries on Glucose Metabolism

for
Post Bariatric Surgery, Gastric Bypass, Sleeve Gastrectomy,
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 18 - 65

Code: NCT02823665

Early_phase1, Recruiting
Active & Responsive

Dynamic Connectivity Under Metabolic Constraints

for
Insulin Resistance, Healthy, Diet Modification, Aging
Location: Charlestown MA, Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18 - 70+

Code: NCT04106882

Recruiting
Active & Responsive

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

for
Early Stage Non-Small Cell Lung Cancer
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT03546829

Phase1, Recruiting
Active & Responsive

Remote Delivery of a Mindfulness-based Intervention for Tics

for
Tourette Syndrome, Tourette's Disorder,
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT06408662

Recruiting
Active & Responsive

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for
Mesial Temporal Lobe Epilepsy
Location: Boston MA, Lebanon NH, Great Neck NY, New York NY,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05135091

Phase3, Recruiting
Active & Responsive

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

for
Somatostatin Receptor Positive, NETs, Lymphoma, Solid Tumor,
Location: Philadelphia PA, Houston TX, San Francisco CA
Sponsor: ITM Solucin GmbH

Sex: All

Age: 2 - 18

Code: NCT06441331

Phase1, Recruiting
Active & Responsive

129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of Exacerbation

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: London
Sponsor: Western University, Canada

Sex: All

Age: 50 - 70+

Code: NCT07192016

Recruiting
Active & Responsive

A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy

for
Phase 1b, Open Label, REC-617, RB1-Negative, Leiomyosarcoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07633756

Phase1, Recruiting
Active & Responsive

Nemtabrutinib With CAR T Therapy in Relapsed/Refractory Mantle Cell Lymphoma

for
Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell Lymphoma
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT07673367

Phase2, Recruiting
Active & Responsive

Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

for
Burns, Contracture Scar, Surgical Injury
Location: Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: All

Age: 18+

Code: NCT06857435

Recruiting
Active & Responsive

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

for
Age-Related Macular Degeneration,
Location: Manchester CT, Beachwood OH, Lemont IL, Tyler TX,
Sponsor: i-Lumen Scientific AUS PTY LTD

Sex: All

Age: 60+

Code: NCT06662162

Recruiting