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Active & Responsive

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Boston MA, New Haven CT, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07111520

Phase1, Phase2, Recruiting
Active & Responsive

Lumateperone for Late-Life Depression

for
Treatment Resistant Depression (TRD),
Location: St Louis MO
Sponsor: Eric Lenze

Sex: All

Age: 60+

Code: NCT07623135

Phase3, Recruiting
Active & Responsive

Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

for
Mild Autonomous Cortisol Secretion (MACS),
Location: Pittsburgh PA
Sponsor: Alaa Sada

Sex: All

Age: 18+

Code: NCT07573163

Phase2, Recruiting
Active & Responsive

Telehealth Music Therapy for Adults With Endocrine Disorder and Depression

for
Type 1 Diabetes, Hashimoto Disease, Graves Disease,
Location: Boone NC
Sponsor: Appalachian State University

Sex: All

Age: 18 - 65

Code: NCT07413874

Recruiting
Active & Responsive

PDT For Induction Therapy For Head And Neck Cancer

for
Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07214987

Phase2, Recruiting

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Active & Responsive

Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study

for
Type 1 Diabetes
Location: Portland ME, Boston MA, New York NY, Detroit MI,
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07676565

Recruiting
Active & Responsive

MedlyPeds Feasibility Study

for
Pediatric Heart Failure, Congenital Heart Disease (CHD),
Location: Toronto
Sponsor: The Hospital for Sick Children

Sex: All

Age: 8 - 18

Code: NCT07556185

Recruiting
Active & Responsive

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

for
Post Traumatic Stress Disorder, PTSD
Location: Rockville MD
Sponsor: Sunstone Medical

Sex: Female

Age: 18+

Code: NCT06902974

Phase2, Recruiting
Active & Responsive

Individualized Diabetes Education Assisted by CGM (IDEA-CGM)

for
Type 2 Diabetes
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18+

Code: NCT06784375

Recruiting
Active & Responsive

KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction

for
Anterior Cruciate Ligament (ACL) Reconstruction Surgery
Location: Chicago IL
Sponsor: Rush University Medical Center

Sex: All

Age: 18+

Code: NCT07090616

Recruiting
Active & Responsive

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

for
Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer,
Location: Hartford CT, New York NY, Englewood NJ, Florham Park NJ,
Sponsor: VM Oncology, LLC

Sex: All

Age: 18 - 70+

Code: NCT03556228

Phase1, Phase2, Recruiting
Active & Responsive

Studying Melatonin and Recovery in Teens

for
Juvenile; Scoliosis, Scoliosis Idiopathic,
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 12 - 18

Code: NCT06093477

Recruiting
Active & Responsive

Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder

for
Nightmare,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06441864

Recruiting
Active & Responsive

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

for
Bipolar I Disorder, Bipolar II Disorder,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 65

Code: NCT07213466

Recruiting
Active & ResponsiveNew

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for
Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT07514819

Recruiting
Active & Responsive

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Boston MA, Atlanta GA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06059391

Phase2, Recruiting
Active & Responsive

Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.

for
Reccurent/Metastatic Solid Tumor Disease,
Location: Quebec
Sponsor: CHU de Quebec-Universite Laval

Sex: Male

Age: 18+

Code: NCT07483658

Recruiting
Active & Responsive

A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07112053

Phase2, Recruiting
Active & Responsive

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for
Bone Pain, Metastatic Malignant Neoplasm in the Bone,
Location: Boston MA, New York NY, Philadelphia PA, Atlanta GA,
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT03858205

Recruiting
Active & Responsive

Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)

for
Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV,
Location: Toronto, Calgary
Sponsor: AstraZeneca

Sex: All

Age: 18

Code: NCT07509151

Phase3, Recruiting