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Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

for
Glioblastoma, IDH-wildtype, Glioblastoma,
Location: Providence RI, New York NY, Durham NC, Cleveland OH,
Sponsor: Orbus Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05879367

Phase1, Recruiting

Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT05423210

Early_phase1, Recruiting

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT00083512

Recruiting

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

for
Glioblastoma Multiforme, Astrocytoma, Grade III
Location: Houston TX
Sponsor: David Baskin MD

Sex: All

Age: 18+

Code: NCT03596086

Phase1, Phase2, Recruiting

MRI Predictors of Response to Tumor Treating Fields

for
Glioblastoma Multiforme
Location: Brooklyn NY
Sponsor: New York Presbyterian Brooklyn Methodist Hospital

Sex: All

Age: 18+

Code: NCT03642080

Recruiting

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Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for
Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06810544

Phase1, Phase2, Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

for
Glioblastoma, Glioblastoma Multiforme, Glioma, Malignant, GBM,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT05271240

Phase3, Recruiting

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

for
Glioblastoma, Glioblastoma, IDH-wildtype,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06146725

Recruiting

Study of Pembrolizumab and M032 (NSC 733972)

for
Glioblastoma Multiforme, Anaplastic Astrocytoma, Gliosarcoma
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT05084430

Phase1, Phase2, Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

for
Glioblastoma, Glioblastoma Multiforme,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06283927

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

for
Glioblastoma, IDH-wildtype, Glioblastoma,
Location: Boston MA, San Francisco CA
Sponsor: Erasmus Medical Center

Sex: All

Age: 0 - 70+

Code: NCT06273176

Recruiting

Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma

for
Glioblastoma, Glioblastoma Multiforme
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05281731

Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

for
Recurrent Glioblastoma,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT07416188

Phase1, Phase2, Recruiting

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma

for
Glioblastoma Multiforme, Glioblastoma
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT05353530

Phase1, Recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma,
Location: Columbus OH, Cincinnati OH
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 21

Code: NCT06333899

Early_phase1, Recruiting

GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma

for
Glioblastoma Multiforme of Brain
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 21 - 70

Code: NCT06815432

Phase1, Recruiting

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

for
Glioblastoma, Brain Cancer, Glioblastoma Multiforme,
Location: New York NY, Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT06991101

Phase2, Recruiting

hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM)

for
Glioblastoma Multiforme, Glioblastoma Multiforme, Adult,
Location: Cleveland OH
Sponsor: Leland Metheny

Sex: All

Age: 18+

Code: NCT05052957

Phase2, Recruiting

Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy

for
GBM, Glioblastoma Multiforme (GBM),
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18 - 70+

Code: NCT07179328

Phase1, Recruiting

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

for
Glioblastoma Multiforme
Location: Los Angeles CA
Sponsor: Chirag G. Patil

Sex: All

Age: 18+

Code: NCT04977375

Phase1, Phase2, Recruiting