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Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Scarborough ME, Worcester MA, Hartford CT, Norwalk CT,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & Responsive

Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors

for
Healthy Volunteers, Pancreatic Ductal Adenocarcinoma,
Location: The Bronx NY
Sponsor: Radiopharm Theranostics, Ltd

Sex: All

Age: 18+

Code: NCT05799274

Phase1, Recruiting
Active & ResponsiveNew

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

for
Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma,
Location: Scottsdale AZ
Sponsor: VM Discovery, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07636785

Phase1, Phase2, Recruiting
Active & ResponsiveNew

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07619599

Phase1, Recruiting
Active & ResponsiveNew

Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, Immunotherapy, Neoadjuvant Therapy
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT06743581

Recruiting

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Active & Responsive

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

for
Adenocarcinoma of Lung, Lung Cancer
Location: Duluth MN, Virginia MN, Hibbing MN, Sandstone MN,
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT04105270

Phase2, Recruiting
Active & Responsive

Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs

for
Lung Cancer Diagnosis, Colorectal Cancer (Diagnosis),
Location: Jamaica NY, New York NY, Brooklyn NY, Staten Island NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06559059

Recruiting
Active & Responsive

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

for
Lung Cancer, Small-cell Lung Cancer, Non Small Cell Lung Cancer
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT05800587

Phase2, Recruiting
Active & Responsive

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

for
Non Small Cell Lung Cancer, Pancreatic Ductal Adenocarcinoma
Location: Fairfax VA, Huntersville NC, Nashville TN,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05431270

Phase1, Phase2, Recruiting
Active & Responsive

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor, Adult, ERBB2 Altered Breast Cancer,
Location: New Haven CT, Lake Success NY, New York NY, Fairfax VA,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07361562

Phase1, Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Philadelphia PA, Fairfax VA, Charlotte NC, Nashville TN,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT06043817

Phase1, Phase2, Recruiting
Active & Responsive

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for
Metastatic Hepatocellular Carcinoma,
Location: New York NY, Pittsburgh PA, Nashville TN, Zion IL,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06427941

Phase1, Phase2, Recruiting
Active & Responsive

Virtual Personalized Exercise Program for Lung Cancer Patients

for
Lung Cancer
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT06540495

Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase1, Phase2, Recruiting
Active & Responsive

Improving Care for Rural Patients With Solid Tumors

for
Lung Cancer, Head and Neck Cancer, Thyroid Cancer,
Location: Greeley CO, Aurora CO, Loveland CO, Fort Collins CO,
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT04916990

Recruiting
Active & Responsive

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

for
Non-Small Cell Carcinoma of Lung, TNM Stage 4,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT03042221

Recruiting
Active & Responsive

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for
NSCLC Adenocarcinoma, Gastroesophageal Cancer (GC),
Location: New York NY, East Brunswick NJ, Philadelphia PA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07277413

Phase1, Recruiting
Active & Responsive

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for
Metastatic Non-small Cell Lung Cancer
Location: Shirley NY, New Hyde Park NY, The Bronx NY, New York NY,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06216301

Phase3, Recruiting
Active & Responsive

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

for
Non-small Cell Lung Cancer
Location: New York NY, Tampa FL, Elizabethtown KY, Birmingham AL
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06841055

Phase2, Recruiting