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Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Boston MA, New Haven CT, New York NY, Baltimore MD,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07349537

Phase1, Recruiting

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Charlottesville VA, Pittsburgh PA, Wesley Chapel FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07012031

Phase1, Phase2, Recruiting

Iadademstat + SBRT With Atezo in ES-SCLC

for
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07113691

Phase1, Recruiting

A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Disease

for
NSCLC, NSCLC, Stage I, NSCLC Stage II,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07323732

Phase2, Recruiting

Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots

for
Breast Cancer, Lung Cancer (Diagnosis), Prostate Cancer
Location: Orlando FL
Sponsor: AdventHealth

Sex: All

Age: 18+

Code: NCT07231159

Recruiting

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A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

for
Head and Neck Squamous Cell Carcinoma HNSCC,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Sutro Biopharma, Inc.

Sex: All

Age: 18+

Code: NCT07227168

Phase1, Recruiting

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

for
Breast Cancer, Cervical Cancer, Bladder Cancer,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 65+

Code: NCT07227077

Recruiting

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for
Extensive-stage Small-cell Lung Cancer
Location: Burlington MA, White Plains NY, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712355

Phase3, Recruiting

New York Better Breathing Study

for
Localized Lung Carcinoma, Stage I Lung Cancer AJCC v8,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06869447

Recruiting

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

for
Small-cell Lung Cancer, Brain Metastases
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18+

Code: NCT07175077

Recruiting

DRP-104 in Patients With NFE2L2/KEAP1-altered Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07249372

Phase2, Recruiting

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Detroit MI, Los Angeles CA
Sponsor: SciTech Development, Inc.

Sex: All

Age: 18+

Code: NCT06922539

Phase1, Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for
Non-Small Cell Lung Cancer
Location: Boston MA, Mineola NY, New York NY, Philadelphia PA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07100080

Phase2, Phase3, Recruiting

Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

for
Renal Cell Carcinoma, Non Small Cell Lung Cancer, Melanoma,
Location: Pittsburgh PA
Sponsor: Diwakar Davar

Sex: All

Age: 18+

Code: NCT07223424

Phase2, Recruiting

Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women

for
Uterine Cancer, Rectal Cancer, Colon Cancer, Breast Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: Female

Age: 18 - 50

Code: NCT06904365

Recruiting

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

for
Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
Location: New York NY, New Brunswick NJ, Morristown NJ,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT04913285

Phase1, Recruiting

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

for
Esophageal Carcinoma, Lung Non-Small Cell Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03948100

Recruiting

A Phase 2 Platform Study of Immunomodulatory Compounds in ICI-refractory Non-small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, ICI-refractory
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07133425

Phase2, Recruiting

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

for
Non-Small-Cell Lung Cancer,
Location: Lake Success NY, New York NY, Philadelphia PA, Ottawa,
Sponsor: ArriVent BioPharma, Inc.

Sex: All

Age: 18+

Code: NCT07185997

Phase3, Recruiting

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

for
Non-small Cell Lung Cancer
Location: Westbrook ME, Farmington CT, Stamford CT, Hackensack NJ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07190248

Phase3, Recruiting