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Active & Responsive

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

for
Alagille Syndrome
Location: New York NY, Memphis TN, St Louis MO, Kansas City MO,
Sponsor: Ipsen

Sex: All

Age: 0+

Code: NCT06850038

Recruiting
Active & Responsive

Photobiomodulation for Pediatric Hypertrophic Tonsils

for
Pediatric Sleep Apnea, Obstructive Sleep Apnea,
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 6 - 12

Code: NCT05459935

Recruiting
Active & Responsive

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

for
Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 3 - 17

Code: NCT06576830

Recruiting
Active & Responsive

Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)

for
Environmental Exposure, Pregnancy Related, Preterm Birth,
Location: Galveston TX
Sponsor: The University of Texas Medical Branch, Galveston

Sex: Female

Age: 18+

Code: NCT07758114

Recruiting
Active & Responsive

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

for
Glioblastoma Multiforme (GBM),
Location: Houston TX
Sponsor: Radiomedix, Inc.

Sex: All

Age: 18+

Code: NCT07733674

Phase1, Recruiting

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Active & Responsive

DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.

for
Obstructive Sleep Apnea (OSA)
Location: West Palm Beach FL, Brandon FL, Anderson SC,
Sponsor: Incannex Healthcare Ltd

Sex: All

Age: 18 - 65

Code: NCT07635563

Phase2, Recruiting
Active & Responsive

Exploring the Use of Phototherapy to Improve CPAP Compliance

for
Obstructive Sleep Apnea
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18+

Code: NCT06960161

Phase1, Recruiting
Active & Responsive

Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion

for
Apnea, Airway Obstruction, Nasal, Mandible Small,
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 8 - 14

Code: NCT04190953

Recruiting
Active & Responsive

Itraconazole Therapy In Bronchiectasis With Airway Mold

for
Bronchiectasis, Fungal Infection of Upper Respiratory Tract
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07283497

Recruiting
Active & Responsive

Brain Blood Vessel Responses to Changes in Blood Flow

for
Magnetic Resonance Imaging, Cerebrovascular Circulation
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 55 - 69

Code: NCT06629077

Phase2, Recruiting
Active & Responsive

Immunogenicity of RSVPreF3 Vaccine in Immunocompromised Persons

for
Respiratory Syncytial Virus (RSV)
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT07050732

Phase2, Recruiting
Active & Responsive

Telehealth for Sleep Apnea: Effectiveness, Implementation, and Cost in the Military Health System

for
Obstructive Sleep Apnea (OSA)
Location: Bethesda MD
Sponsor: Uniformed Services University of the Health Sciences

Sex: All

Age: 18 - 64

Code: NCT07121452

Recruiting
Active & Responsive

Gene Therapy for Alpha 1- Antitrypsin Deficiency

for
Alpha 1-Antitrypsin Deficiency
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18 - 70

Code: NCT06996756

Phase1, Recruiting
Active & Responsive

Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea

for
Obstructive Sleep Apnea
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18+

Code: NCT06960200

Phase2, Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: Halifax, Boston MA, New York NY, Philadelphia PA,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase3, Recruiting
Active & Responsive

Autus Valve Continued Access Study (CAS)

for
Congenital Heart Disease
Location: Ann Arbor MI
Sponsor: Edwards Lifesciences

Sex: All

Age: 1 - 16

Code: NCT07466745

Recruiting
Active & Responsive

An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for
Stomatitis
Location: Wynnewood PA, East Syracuse NY, Wilson NC, Athens GA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07357597

Recruiting
Active & Responsive

A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

for
IO-resistant sqNSCLC
Location: Margate FL, Tamarac FL, Jonesboro AR, Houston TX,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07217301

Phase3, Recruiting
Active & Responsive

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

for
Malignant Neoplasm
Location: Clermont FL, Fargo ND, Sioux Falls SD
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07252739

Phase2, Recruiting
Active & Responsive

Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF)

for
Cystic Fibrosis
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 16+

Code: NCT04002882

Recruiting