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Active & Responsive

Left vs. Right Non-Inferiority Trial

for
Depression, Major Depressive Disorder, Major Depressive Episode
Location: Toronto, Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 18 - 65

Code: NCT04999553

Recruiting
Active & Responsive

Mechanisms of Rumination Change in Adolescent Depression

for
Major Depressive Disorder, Mood Disorders
Location: Columbus OH, Salt Lake City UT
Sponsor: Ohio State University

Sex: All

Age: 14 - 17

Code: NCT03859297

Recruiting
Active & Responsive

Sleep TMS for Depression

for
Major Depression, Sleep
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18 - 65

Code: NCT06824415

Recruiting
Active & Responsive

Transcranial Direct Current Stimulation for Depression

for
Unipolar Depression
Location: Woodbridge NJ
Sponsor: Soterix Medical

Sex: All

Age: 22+

Code: NCT07042217

Recruiting
Active & Responsive

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

for
Depressive Disorder, Major
Location: Boston MA, Watertown MA, Foxborough MA, Levis,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07412756

Phase3, Recruiting

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Active & Responsive

Biomarkers of Depression and Treatment Response

for
Depressive Disorder, Major
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18 - 70

Code: NCT04581902

Recruiting
Active & Responsive

Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression

for
Depression, Depressive Disorder, Major
Location: Ottawa
Sponsor: The Royal Ottawa Mental Health Centre

Sex: All

Age: 16 - 19

Code: NCT06528938

Recruiting
Active & Responsive

Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans

for
Major Depression Disorder, Depression
Location: West Haven CT
Sponsor: Deepak C. D'Souza

Sex: All

Age: 21 - 65

Code: NCT06671977

Phase1, Recruiting
Active & Responsive

RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)

for
Unipolar Depression, Bipolar Depression
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 65

Code: NCT07266545

Recruiting
Active & Responsive

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

for
Major Depression
Location: Philadelphia PA, Birmingham AL, Tuscaloosa AL,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18 - 70+

Code: NCT07226232

Phase3, Recruiting
Active & Responsive

Nebulized Ketamine for the Treatment of Major Depressive Disorder

for
Severe Depression, Moderate Depression, Ketamine, Midazolam,
Location: Brooklyn NY
Sponsor: Theresa Jacob, PhD, MPH

Sex: All

Age: 18 - 70+

Code: NCT06752759

Phase3, Recruiting
Active & Responsive

The Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Major Depressive Disorder

for
Depression, Treatment Resistant Depression
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18 - 65

Code: NCT04805879

Phase2, Phase3, Recruiting
Active & Responsive

InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI

for
TBI (Traumatic Brain Injury), Depressive Disorder, Major,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18 - 64

Code: NCT06005194

Recruiting
Active & Responsive

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

for
Bipolar II Disorder,
Location: San Francisco CA
Sponsor: Andrew Krystal

Sex: All

Age: 22 - 70

Code: NCT07127913

Recruiting
Active & ResponsiveNew

One-Day cTBS Over the Precuneus

for
Depressive Disorder, Treatment-Resistant,
Location: Belmont MA
Sponsor: Mclean Hospital

Sex: All

Age: 18+

Code: NCT07758010

Recruiting
Active & Responsive

Treating Major Depression With Yoga Mono-therapy

for
Depression Mild, Depression Moderate
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06091527

Recruiting
New

An Evaluation of the Impact of Pharmacist Comprehensive Medication Management With Pharmacogenomic Results to Improve Depression Outcomes in Community Pharmacies.

for
Pharmacogenetics, Depression - Major Depressive Disorder,
Location: Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: All

Age: 18+

Code: NCT07373470

Recruiting
New

Near Infrared Spectroscopy (NIRS) for Assessment of Depression

for
Major Depressive Disorder
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT04061148

Recruiting

Amygdala Neurofeedback for Depression - Large Scale Clinical Trial

for
Major Depressive Disorder
Location: Pittsburgh PA
Sponsor: Kymberly Young

Sex: All

Age: 18 - 55

Code: NCT05703256

Recruiting

Peripheral Neuroimmune Mechanisms of Hyperthermia

for
Hyperthermia, Major Depressive Disorder, Inflammation
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 65

Code: NCT05366270

Recruiting