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Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

for
Clinical Stage IA Cutaneous Melanoma AJCC v8,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06673095

Recruiting

A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma

for
Uveal Melanoma, Melanoma, Metastatic Uveal Melanoma,
Location: Harrison NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05607095

Phase1, Recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Providence RI, New Haven CT, Lebanon NH, Quebec,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase3, Recruiting

Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma

for
Cutaneous Melanoma, Melanoma Stage IV, Mucosal Melanoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06319196

Phase2, Recruiting

Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

for
Lung Non-Small Cell Carcinoma, Malignant Solid Neoplasm,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05830058

Phase2, Recruiting

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Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

for
Ankylosing Spondylitis, Autoimmune Disease, Crohn Disease,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04751396

Recruiting

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

for
Mucosal Melanoma
Location: Harrison NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05384496

Phase2, Recruiting

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

for
Cancer, All Types, Cancer of Liver, Cancer of Stomach,
Location: Gainesville GA
Sponsor: SpeciCare

Sex: All

Age: 0 - 70+

Code: NCT03896958

Recruiting

A Study of NX-1607 in Adults With Advanced Malignancies

for
Ovarian Cancer, Epithelial, Gastric Cancer,
Location: Charlottesville VA, Chapel Hill NC, Chicago IL,
Sponsor: Nurix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05107674

Phase1, Recruiting

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for
Melanoma, Cutaneous Malignant
Location: Boston MA, New Haven CT, New York NY, Morristown NJ,
Sponsor: Immatics US, Inc.

Sex: All

Age: 18+

Code: NCT06743126

Phase3, Recruiting

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

for
Advanced Malignancies, Ovarian Cancer, T-cell Lymphoma,
Location: New York NY, Philadelphia PA, Duarte CA
Sponsor: BioInvent International AB

Sex: All

Age: 18+

Code: NCT04752826

Phase1, Phase2, Recruiting

MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors

for
Melanoma
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT05373823

Recruiting

Evaluation for NCI Surgery Branch Clinical Research Protocols

for
Synovial Cell Cancer, Melanoma, Colorectal Cancer, Lung Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT00001823

Recruiting

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Austin TX, San Antonio TX, Scottsdale AZ
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT05094804

Phase1, Phase2, Recruiting

Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic

for
COVID-19 Infection, Melanoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT04474301

Recruiting

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

for
Advanced Melanoma
Location: Bethesda MD, Hialeah FL, Toronto, Pittsburgh PA,
Sponsor: Eikon Therapeutics

Sex: All

Age: 18+

Code: NCT06697301

Phase2, Phase3, Recruiting

Excision of Lymph Node Trial (EXCILYNT) (Mel69)

for
Melanoma
Location: New York NY, Charlottesville VA, Durham NC, Atlanta GA,
Sponsor: Craig L Slingluff, Jr

Sex: All

Age: 18+

Code: NCT05839912

Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 16+

Code: NCT05269381

Phase1, Phase2, Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

for
Melanoma, Lymphoma, Solid Tumor, Classical Hodgkin Lymphoma,
Location: Boston MA, New York NY, Chicago IL, Fargo ND,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 17

Code: NCT02332668

Phase1, Phase2, Recruiting