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Active & Responsive

Siemens Biomarker Multi-modality

for
Fatty Liver, Hepatic Steatosis
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07495332

Recruiting
Active & Responsive

Multi-Site Trial of Tirzepatide for Smoking Cessation

for
Smoking Cessation, Smoking Behaviors
Location: New Haven CT, Chicago IL, Aurora CO, Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 21 - 65

Code: NCT07602699

Phase2, Recruiting
Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: Boston MA, Nashua NH, New York NY, Woodbury NY,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & Responsive

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for
Pulmonary Hypertension, Interstitial Lung Disease (ILD)
Location: Boston MA, New York NY, Philadelphia PA, Richmond VA,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT06911632

Recruiting
Active & Responsive

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

for
Huntington's Disease
Location: Baltimore MD, Washington D.C. DC, Ottawa, Toronto,
Sponsor: University College, London

Sex: All

Age: 11 - 70+

Code: NCT02855476

Recruiting

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Active & Responsive

Platelet Volunteers, Longitudinal and Multi-omic Study

for
Thrombosis
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT07137429

Recruiting
Active & Responsive

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

for
Barrett Esophagus, Gastroesophageal Reflux,
Location: Baltimore MD, Chapel Hill NC, Cleveland OH, Aurora CO
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 50+

Code: NCT06687603

Recruiting
Active & Responsive

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

for
Diabetic Foot Ulcer, Foot Ulcer Chronic, DFU, Ulcer Foot,
Location: Philidelphia PA
Sponsor: BioLab Holdings

Sex: All

Age: 18+

Code: NCT07364630

Recruiting
Active & Responsive

Multi-session fMRI-Neurofeedback in PTSD

for
Post Traumatic Stress Disorder
Location: London
Sponsor: Andrew Nicholson

Sex: All

Age: 18 - 65

Code: NCT05456958

Recruiting
Active & Responsive

Multi-Target Pallidal and Thalamic Deep Brain Stimulation for Hemi-Dystonia

for
Dystonia, Dystonia, Secondary
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 18 - 65

Code: NCT02982304

Phase1, Recruiting
Active & Responsive

Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?

for
POTS - Postural Orthostatic Tachycardia Syndrome
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: Female

Age: 12 - 21

Code: NCT06616363

Recruiting
Active & Responsive

A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation

for
Colorectal Cancer, Advanced Adenocarcinoma
Location: Raonoke VA
Sponsor: Universal Diagnostics

Sex: All

Age: 45 - 70+

Code: NCT06059963

Recruiting
Active & Responsive

Multi-Center PAMPA Study

for
Psoriasis
Location: St. John's, Boston MA, New York NY, Rochester NY,
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT05004727

Recruiting
Active & Responsive

Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families

for
Racially/Ethnically Diverse Families From Urban Settings
Location: Athens GA, Minneapolis MN
Sponsor: University of Colorado, Denver

Sex: All

Age: 8 - 18

Code: NCT05744973

Recruiting
Active & Responsive

Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.

for
Dentin Hypersensitivity, Erosive Tooth Wear
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07195357

Recruiting
Active & Responsive

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

for
Otitis Media With Effusion, Acute Otitis Media, Otitis Media
Location: New York NY, New Brunswick NJ, Cherry Hill NJ,
Sponsor: Smith & Nephew, Inc.

Sex: All

Age: 0 - 17

Code: NCT05915078

Recruiting
Active & Responsive

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

for
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
Location: Worcester MA, Charlottesville VA, Ann Arbor MI,
Sponsor: University of Massachusetts, Worcester

Sex: All

Age: 18 - 70+

Code: NCT06855329

Recruiting
Active & Responsive

Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease

for
Parkinson Disease, Depression, PARKINSON DISEASE (Disorder)
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 40 - 70+

Code: NCT05568498

Phase2, Recruiting
Active & Responsive

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for
Frontotemporal Lobar Degeneration (FTLD),
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04363684

Recruiting
Active & Responsive

Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders

for
Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder,
Location: Kingston, Toronto, Hamilton, London, Edmonton, Calgary
Sponsor: Holland Bloorview Kids Rehabilitation Hospital

Sex: All

Age: 8 - 17

Code: NCT06081348

Phase2, Recruiting