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Palbociclib & Tazemetostat

Recruiting
PHASE1

Sponsor:

Thomas Jefferson University

Location:

Philadelphia PA

Code:

NCT05627232

Conditions

Recurrent Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tazemetostat

Liposome-encapsulated Daunorubicin-Cytarabine

Bone Marrow Aspiration and Biopsy

Biospecimen Collection

Palbociclib

RZ358

Recruiting
PHASE3

Sponsor:

Rezolute

Location:

Philadelphia PA, Saskatoon

Code:

NCT06208215

Conditions

Congenital Hyperinsulinism

Eligibility Criteria

Sex: All

Age: 3 - 45

Healthy Volunteers: Not accepted

Interventions

RZ358 (5 mg/kg) + SOC (Standard-of-Care) or Placebo + SOC

RZ358 (10 mg/kg) or Placebo + SOC

RZ358 (5-10 mg/kg) + SOC

Low-level Red-light Therapy

Recruiting

Sponsor:

UCLA

Location:

San Francisco CA

Code:

NCT05606237

Conditions

Myopia

Eligibility Criteria

Sex: All

Age: 8 - 13

Healthy Volunteers: Accepted

Interventions

Low-level Red Light Therapy Device

CAR T-Cells

Recruiting
EARLY_PHASE1

Sponsor:

UNC Lineberger Comprehensive Cancer Center

Location:

Chapel Hill NC

Code:

NCT05620342

Conditions

Lung Cancer

Small Cell Lung Carcinoma

Non Small Cell Lung Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

iC9.GD2.CAR.IL-15 T Infusion

Obinutuzumab & CC-99282

Recruiting
PHASE2

Sponsor:

M.D. Anderson Cancer Center

Location:

Houston TX

Code:

NCT06108232

Conditions

Follicular Lymphoma

Tumor

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Obinutuzumab

CC-99282

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Observational Study

Recruiting

Sponsor:

Thomas Jefferson University

Location:

Philadelphia PA

Code:

NCT05108233

Conditions

Malignant Head and Neck Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Survey Administration

Revlimid & Rituximab

Recruiting
PHASE2

Sponsor:

Chronic Lymphocytic Leukemia Research Consortium

Location:

La Jolla CA, Boston MA, New Hyde Park NY, Houston TX

Code:

NCT00628238

Conditions

Chronic Lymphocytic Leukemia

CLL

Untreated

Front-line

First-Line

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Lenalidomide and Rituximab

Observational Study

Recruiting

Sponsor:

Ohio State University Comprehensive Cancer Center

Location:

Columbus OH

Code:

NCT06208202

Conditions

Abuse Tobacco

Exposure

Eligibility Criteria

Sex: All

Age: 21 - 29

Healthy Volunteers: Accepted

Interventions

Behavioral Intervention

Biospecimen Collection

Survey Administration

Alcohol & Health

Recruiting

Sponsor:

University of Washington

Location:

Seattle WA

Code:

NCT05620849

Conditions

Sexual Behavior

Alcohol Drinking

Condomless Sex

Eligibility Criteria

Sex: Female

Age: 18 - 24

Healthy Volunteers: Accepted

Interventions

Online program

Nutritional Supplement

Recruiting

Sponsor:

University of British Columbia

Location:

Vancouver

Code:

NCT05602324

Conditions

Severe Infection

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Not accepted

Interventions

Lauric Acid and Berberine