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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, Shirley NY, New Haven CT, Lebanon NH,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase2, Recruiting

A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC

for
Carcinoma, Non-Small-Cell Lung
Location: Toronto, Portland OR, Irvine CA, Duarte CA
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07586202

Phase2, Recruiting

A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Location: Omaha NE
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT05242965

Phase2, Recruiting

A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: New York NY, Fairfax VA, Toronto
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07227025

Phase1, Phase2, Recruiting

Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study

for
Lung Non-Small Cell Carcinoma
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07339254

Recruiting

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Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Columbus OH
Sponsor: Dwight Owen

Sex: All

Age: 18+

Code: NCT06616623

Phase1, Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for
Carcinoma, Non-Small-Cell Lung
Location: White Plains NY, Schenectady NY, Montreal, Newark DE,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06875310

Phase3, Recruiting

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Unipolar Depression
Location: Columbus OH
Sponsor: Alan Davis

Sex: All

Age: 18+

Code: NCT07216404

Phase2, Recruiting

Retifanlimab and Ruxolitinib In Solid Malignancies

for
Non Small Cell Lung Carcinoma, Renal Cell Carcinoma
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 0+

Code: NCT07219576

Phase1, Phase2, Recruiting

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Charlottesville VA, Pittsburgh PA, Wesley Chapel FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07012031

Phase1, Phase2, Recruiting

Impact of Circadian Rhythm on Immunotherapy

for
Advanced/Metastatic NSCLC
Location: Pittsburgh PA
Sponsor: Liza Villaruz, MD

Sex: All

Age: 18+

Code: NCT07224971

Phase2, Recruiting

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

for
Stage IV NSCLC, NSCLC, Immunotherapy, Fasting Mimicking Diet
Location: Indianapolis IN, Chicago IL, St Louis MO, Long Beach CA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT06671613

Recruiting

LUNG-05: Investigating Chemotherapy Effectiveness for Non-Small Cell Lung Cancer (NSCLC) Metastatic Patients

for
NSCLC
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT06576635

Recruiting

Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04780568

Phase1, Recruiting

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

for
Esophageal Carcinoma, Lung Non-Small Cell Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03948100

Recruiting

Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD

for
Lung Non-Small Cell Carcinoma
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07186699

Recruiting

A Study of LY4175408 in Participants With Advanced Cancer

for
Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma,
Location: Boston MA, New York NY, Hackensack NJ, Fairfax VA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07046923

Phase1, Recruiting

A Study of a New PET Scanner in People With Cancer

for
Non Small Cell Lung Carcinoma NSCLC, Head and Neck Cancer,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07690917

Recruiting

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

for
Lung Non-Small Cell Carcinoma
Location: Stony Brook NY, Neptune City NJ, Red Bank NJ, Brick NJ,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07388524

Phase3, Recruiting

Prehabilitation Physical Therapy and Relaxation Intervention Program to Promote Resiliency and Operative Success Among Adults Receiving Lung Cancer Surgery, ROAR-LCS Trial

for
Resectable Lung Non-Small Cell Carcinoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07584239

Recruiting