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A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

for
NSCLC (Non-small Cell Lung Cancer), Solid Tumor
Location: Fairfax VA
Sponsor: Yuhan Corporation

Sex: All

Age: 18+

Code: NCT06616766

Phase1, Phase2, Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for
Ovarian Cancer, Breast Cancer, Endometrial Cancer,
Location: Boston MA, Philadelphia PA, Falls Church VA, Buffalo NY,
Sponsor: NextCure, Inc.

Sex: All

Age: 18+

Code: NCT06774963

Phase1, Recruiting

A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

for
Non-small Cell Lung Cancer
Location: New York NY, Tampa FL, Athens GA, Des Moines IA,
Sponsor: Teligene US

Sex: All

Age: 18+

Code: NCT06010329

Phase2, Recruiting

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

for
Non Small Cell Lung Cancer, Small Cell Lung Carcinoma,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 15+

Code: NCT05265429

Recruiting

Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05424029

Recruiting

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Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics

for
Non Small Cell Lung Cancer, Healthy
Location: Dallas TX
Sponsor: OncoHost Ltd.

Sex: All

Age: 18+

Code: NCT05736029

Recruiting

Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IB (Resectable),
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT06250829

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for
Non-small Cell Lung Cancer
Location: Halifax, Stamford CT, Trois-Rivieres, Albany NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06345729

Phase3, Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for
Multiple Myeloma, Lymphoma, Non-Hodgkin,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02682667

Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, Montreal, Toronto, Jacksonville FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06562192

Phase1, Recruiting

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for
Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06810544

Phase1, Phase2, Recruiting

A Beta-only IL-2 ImmunoTherapY Study

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boca Raton FL, Toronto, Detroit MI, Atlanta GA,
Sponsor: Medicenna Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05086692

Phase1, Phase2, Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma,
Location: East Brunswick NJ, Philadelphia PA, York PA,
Sponsor: Guardant Health, Inc.

Sex: All

Age: 18+

Code: NCT05059444

Recruiting

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for
Solid Tumor, Adult, Triple Negative Breast Cancer,
Location: Scottsdale AZ, La Jolla CA, Stanford CA
Sponsor: BioEclipse Therapeutics

Sex: All

Age: 18+

Code: NCT04282044

Phase1, Recruiting

Synapse 3D With Intravascular Indocyanine Green

for
Non-small Cell Lung Cancer, Primary Neoplasm
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT03953144

Phase1, Phase2, Recruiting

A Study of Lorlatinib in Advanced ALK and ROS1 Rearranged Lung Cancer With CNS Metastasis in the Absence of Measurable Extracranial Lesions

for
Non-Small Cell Lung Cancer (NSCLC)
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT02927340

Phase2, Recruiting

Using Urine Samples to Identify Lung Cancer

for
Non Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT06033248

Recruiting

Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

for
Non-small Cell Lung Cancer
Location: Syracuse NY
Sponsor: State University of New York - Upstate Medical University

Sex: All

Age: 18+

Code: NCT02619448

Early_phase1, Recruiting

Study of Carboplatin/Gemcitabine Plus Bevacizumab in Advanced Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Southfield MI
Sponsor: St. John Providence Health System

Sex: All

Age: 18+

Code: NCT00150657

Phase2, Recruiting

Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

for
Muscle-Invasive Bladder Carcinoma,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06529822

Phase1, Recruiting