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A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

for
Mature B-Cell Non-Hodgkin Lymphoma
Location: Boston MA, New York NY, Baltimore MD, Cincinnati OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 30

Code: NCT05533775

Phase1, Phase2, Recruiting
Active & Responsive

Multisite Implementation of COMPRENDO

for
Pediatric Cancer
Location: Boston MA, Birmingham AL, San Diego CA,
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT06055296

Recruiting
Active & Responsive

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

for
Cancer, Breast Cancer, Lung Cancer, Colon Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03702309

Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Scarborough ME, Worcester MA, Hartford CT, Norwalk CT,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & ResponsiveNew

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for
Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT07514819

Recruiting

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Active & Responsive

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

for
Glioblastoma Multiforme (GBM), Glioblastoma, Glioma of Brain,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18 - 70+

Code: NCT03213002

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase1, Phase2, Recruiting
Active & Responsive

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

for
Localized Renal Pelvis and Ureter Urothelial Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: Male

Age: 18+

Code: NCT01050504

Recruiting
Active & Responsive

A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer

for
Breast Cancer, Breast Neoplasm, Breast Cancer Stage IV
Location: Sarasota FL, Nashville TN, Beverly Hills CA
Sponsor: MBQ Pharma

Sex: All

Age: 21+

Code: NCT06075810

Phase1, Recruiting
Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase1, Phase2, Recruiting
Active & Responsive

A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Upland CA, Irvine CA, Lancaster CA, Duarte CA,
Sponsor: City of Hope Medical Center

Sex: Female

Age: 18+

Code: NCT07741968

Recruiting
Active & Responsive

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07619599

Phase1, Recruiting
Active & Responsive

Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.

for
Reccurent/Metastatic Solid Tumor Disease,
Location: Quebec
Sponsor: CHU de Quebec-Universite Laval

Sex: Male

Age: 18+

Code: NCT07483658

Recruiting
Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Boston MA, New Haven CT, Lake Success NY, The Bronx NY,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase2, Recruiting
Active & Responsive

Surviving Daily Life

for
Stress, Cognitive Change, Breast Cancer, Breast Carcinoma,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: Female

Age: 40+

Code: NCT07054723

Recruiting
Active & Responsive

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

for
Breast Cancer, Breast Neoplasm, Breast Tumor,
Location: New York NY, Hampton VA, Baltimore MD, Fairfax VA,
Sponsor: Proton Collaborative Group

Sex: Female

Age: 50+

Code: NCT01766297

Phase2, Recruiting
Active & Responsive

Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO)

for
Pediatric Brain Tumor, Pediatric Spine Tumor
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 1 - 17

Code: NCT06981156

Recruiting
Active & Responsive

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for
Non-small Cell Lung Cancer, Histiocytic Neoplasm, Histiocytosis,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT05786924

Phase1, Phase2, Recruiting
Active & Responsive

STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer

for
Malignant Neoplasm of Prostate,
Location: Cleveland OH
Sponsor: Angela Y. Jia, MD PhD

Sex: Male

Age: 18+

Code: NCT06574880

Phase1, Phase2, Recruiting