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The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

for
Patients Undergoing Routine Health Care, Heart Diseases,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT01280825

Recruiting

Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05772130

Recruiting

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

for
Acute Graft Versus Host Disease,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05443425

Phase1, Recruiting

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

for
Osteosarcoma, Pulmonary Metastasis, Fluorescence,
Location: Chicago IL
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All

Age: 6 - 17

Code: NCT06235125

Phase1, Recruiting

A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

for
Malignant Neoplasm
Location: Fairfax VA, Houston TX, San Antonio TX
Sponsor: Tyligand Pharmaceuticals (Suzhou) Limited

Sex: All

Age: 18 - 70+

Code: NCT06385925

Phase1, Phase2, Recruiting

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Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

for
Malignant Oral Cavity Neoplasm, Malignant Skull Base Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04265430

Recruiting

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

for
Astrocytoma, Glioma, Recurrent Glioblastoma
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06344130

Phase1, Recruiting

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

for
Chronic Lymphocytic Leukemia,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0+

Code: NCT06151730

Recruiting

A Study to Give Treatment Inside the Eye to Treat Retinoblastoma

for
Bilateral Retinoblastoma, Childhood Intraocular Retinoblastoma,
Location: Montreal, Durham NC, Akron OH, Cleveland OH, Atlanta GA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 18

Code: NCT05504291

Phase2, Recruiting

Evaluation of the Pathobiology of CALR-mutated MPN Cells

for
Myeloproliferative Neoplasm
Location: Winston-Salem NC, Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06480591

Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

for
Anaplastic Astrocytoma, IDH-Wildtype,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04623931

Phase2, Recruiting

Molecular Analysis of Suspected or High-Risk Lung Cancer to Drive Individualized Care

for
Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06482073

Recruiting

Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study

for
Pancreatic Neoplasm
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05961982

Recruiting

Study of Olutasidenib and Temozolomide in HGG

for
High Grade Glioma, Astrocytoma, Astrocytoma, Grade III,
Location: Durham NC, Miami FL, Columbus OH, Cincinnati OH,
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 12 - 39

Code: NCT06161974

Phase2, Recruiting

Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions

for
Pleural Neoplasm
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03465774

Recruiting

An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors

for
Childhood Malignant Solid Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0 - 17

Code: NCT06915727

Phase3, Recruiting

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

for
Glioblastoma, Recurrent Glioblastoma, Brain Tumor
Location: Boston MA
Sponsor: Ugonma Chukwueke

Sex: All

Age: 18+

Code: NCT06552260

Early_phase1, Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06565260

Recruiting

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

for
Breast Carcinoma, Esophageal Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00991094

Recruiting