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A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

for
Accelerated Phase Myeloproliferative Neoplasm,
Location: New York NY, Richmond VA, North Miami FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06661915

Phase2, Recruiting

Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams

for
Malignant Solid Neoplasm
Location: Little Rock AR
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07278739

Recruiting

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05111561

Phase1, Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

for
Acute Lymphocytic Leukemia (ALL), Acute Myeloid Leukemia (AML),
Location: Pittsburgh PA
Sponsor: Sawa Ito, MD

Sex: All

Age: 18+

Code: NCT07565220

Phase1, Recruiting

Quality of End-of-Life Care for Children With Cancer

for
Childhood Hematopoietic and Lymphatic System Neoplasm,
Location: Providence RI, The Bronx NY, Albany NY, Wilmington DE,
Sponsor: Children's Oncology Group

Sex: All

Age: 18+

Code: NCT07412002

Recruiting

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Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms

for
Appendiceal Mucinous Neoplasm, Pseudomyxoma Peritonei
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07693452

Phase2, Recruiting

BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants

for
Chronic Kidney Disease, Stage 4,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18 - 65

Code: NCT06741072

Phase1, Recruiting

Caris Chromoseq Data Collection

for
Acute Myeloid Leukemia (AML),
Location: Phoenix AZ
Sponsor: Caris Science, Inc.

Sex: All

Age: 18+

Code: NCT07680868

Recruiting

Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)

for
Glioblastoma (GBM)
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07375992

Recruiting

Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cystic Neoplasms

for
Pancreatic Cystic Neoplasm
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07529483

Phase2, Recruiting

Randomization for the Identification of Best Treatment Intensity for Less Fit Adults With Acute Myeloid Leukemia and Myeloid Neoplasms

for
Acute Leukemia of Ambiguous Lineage, Acute Myeloid Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07094750

Recruiting

Chemoimmunotherapy for ALK+ Relapsed/Refractory ALCL

for
Anaplastic Large Cell Lymphoma, ALK-Positive
Location: Valhalla NY
Sponsor: New York Medical College

Sex: All

Age: 1 - 39

Code: NCT07013565

Phase2, Recruiting

Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma

for
Meningioma of Brain, Meningioma, Brain Tumor
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT07418775

Recruiting

An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

for
Malignant Brain Neoplasm
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06667726

Phase2, Recruiting

Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology

for
Malignant Solid Neoplasm, Hematopoietic Neoplasms,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 15+

Code: NCT06897137

Recruiting

N-803 in Patients With Progressive Synovial Sarcoma and Myxoid/Round Cell Liposarcoma Previously Treated With Adoptive Cellular Therapy

for
Myxoid Liposarcoma, Round Cell Liposarcoma, Synovial Sarcoma
Location: Chicago IL
Sponsor: Seth Pollack

Sex: All

Age: 18 - 70+

Code: NCT07261657

Early_phase1, Recruiting

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for
Anaplastic Large Cell Lymphoma, ALK-Negative,
Location: Millville DE, Lewes DE, Rehoboth Beach DE,
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18 - 70+

Code: NCT06724237

Phase3, Recruiting

A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.

for
CNS Malignancies, Medulloblastoma Recurrent, ATRT Recurrent,
Location: Washington D.C. DC
Sponsor: Children's National Research Institute

Sex: All

Age: 3 - 21

Code: NCT07017816

Early_phase1, Recruiting

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for
Recurrent Glioblastoma, IDH-Wildtype,
Location: New York NY, Livingston NJ, New Brunswick NJ,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05432804

Phase1, Phase2, Recruiting

Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease

for
Chronic Graft Versus Host Disease,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07535008

Recruiting