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Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1

for
Synovial Sarcoma, Myxoid/Round Cell Liposarcoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 16 - 70+

Code: NCT06083883

Phase1, Recruiting

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

for
Lung Neoplasm
Location: Boston MA, Baltimore MD, Durham NC, Miami FL,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT02984761

Recruiting

Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for
Malignant Solid Neoplasm
Location: Providence RI, New Haven CT, Lebanon NH, Fairfield CT,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05642611

Phase3, Recruiting

2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers

for
Malignant Digestive System Neoplasm
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT03800693

Phase2, Recruiting

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

for
Solid Tumor, Sarcoma, Leiomyosarcoma,
Location: Boston MA, Lake Success NY, Fairfax VA, Grand Rapids MI,
Sponsor: STORM Therapeutics LTD

Sex: All

Age: 18+

Code: NCT06975293

Phase1, Phase2, Recruiting

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Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

for
Clinical Stage IV Cutaneous Melanoma AJCC v8,
Location: Columbus OH
Sponsor: Kari Kendra

Sex: All

Age: 18+

Code: NCT05588453

Phase1, Phase2, Recruiting

Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors

for
Primary Brain Neoplasm
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 19+

Code: NCT03830151

Phase1, Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Boston MA, Providence RI, Westerly RI, Waterford CT,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase3, Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

for
Endocrine Tumors, Thyroid Neoplasms, Parathyroid Neoplasms,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 4+

Code: NCT01005654

Recruiting

Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

for
High Grade Astrocytic Tumor,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05465954

Phase2, Recruiting

Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors

for
Malignant Neoplasm of Breast
Location: New Haven CT, Buffalo NY, Rancho Mirage CA, La Jolla CA
Sponsor: Novian Health Inc.

Sex: Female

Age: 18+

Code: NCT03463954

Recruiting

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma,
Location: Washington D.C. DC, Durham NC, Columbus OH,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 39

Code: NCT05843253

Phase2, Recruiting

Social Determinants of Health in Hepatobiliary Cancer Patients

for
Malignant Hepatobiliary Neoplasm
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06053333

Recruiting

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

for
Glioblastoma Multiforme
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18 - 70+

Code: NCT05083754

Phase1, Recruiting

A Phase 1 Study of Neoadjuvant Abemaciclib in Combination With Radiation Therapy for Liposarcomas

for
Retroperitoneal Sarcoma, Liposarcoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06025747

Phase1, Recruiting

Evaluation of Portal Vein Stenting in Patients With Portal Vein Stenosis and Gastrointestinal Cancers

for
Malignant Digestive System Neoplasm
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04629677

Recruiting

Evaluation of the CONVIVO System

for
Glioblastoma, Glial Tumor, Brain Metastases, Meningioma,
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18+

Code: NCT05139277

Recruiting

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

for
Neuroblastoma
Location: Hartford CT, Quebec, Sherbrooke, Montreal, Hershey PA,
Sponsor: Giselle Sholler

Sex: All

Age: 0 - 22

Code: NCT02559778

Phase2, Recruiting

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

for
Glioma, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT01772771

Recruiting

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry

for
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Location: Ottawa, Miami FL, Tampa FL, Calgary, Seattle WA
Sponsor: Immune Oncology Research Institute

Sex: All

Age: 0+

Code: NCT05430971

Recruiting