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Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

for
Glioblastoma, Recurrent Glioblastoma,
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06613841

Early_phase1, Recruiting

Personalized NK Cell Therapy in CBT

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 15 - 70+

Code: NCT02727803

Phase2, Recruiting

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

for
Primary Brain Tumor, Glioma, Meningioma, Schwannoma
Location: San Diego CA
Sponsor: Jona Hattangadi-Gluth

Sex: All

Age: 18 - 70+

Code: NCT05576103

Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Halifax, Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase2, Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, New Haven CT, Valhalla NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 25

Code: NCT06395103

Phase1, Phase2, Recruiting

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Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06949943

Recruiting

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

for
Recurrent Gliosarcoma, Recurrent Supratentorial Glioblastoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT04991870

Phase1, Recruiting

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for
Acral Lentiginous Melanoma,
Location: Jacksonville NC, Goldsboro NC, Clinton NC,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04511013

Phase2, Recruiting

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

for
Metastatic Soft Tissue Sarcoma,
Location: New York NY, Miami FL, Houston TX, Aurora CO
Sponsor: Adcendo ApS

Sex: All

Age: 18+

Code: NCT06797999

Phase1, Phase2, Recruiting

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for
Childhood Extracranial Germ Cell Tumor,
Location: St. John's, Halifax, Bangor ME, Portland ME,
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT03067181

Phase3, Recruiting

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

for
B-ALL, Hematologic Malignancy, Solid Tumor
Location: Philadelphia PA, Milwaukee WI, Memphis TN, Aurora CO,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 30

Code: NCT06579469

Recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for
Central Nervous System Nongerminomatous Germ Cell Tumor,
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT04684368

Phase2, Recruiting

Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers

for
Lymphoma, B-Cell, Lymphoma, Large-cell Lymphoma,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05940272

Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Location: Boston MA, Providence RI, Burlington MA, New Haven CT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06119581

Phase3, Recruiting

Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia

for
Myelodysplastic Syndromes, Acute Myeloid Leukemia,
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18+

Code: NCT06599762

Phase2, Recruiting

Project: Every Child for Younger Patients With Cancer

for
Adrenal Gland Pheochromocytoma, Carcinoma In Situ,
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT02402244

Recruiting

Cognitive Biomarkers in Pediatric Brain Tumor Patients

for
Childhood Brain Tumor
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 4 - 18

Code: NCT02914067

Recruiting

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for
Metastatic Malignant Neoplasm in the Lung,
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 50

Code: NCT05235165

Phase3, Recruiting

A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma

for
Well Differentiated Liposarcoma, Dedifferentiated Liposarcoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06843967

Phase1, Phase2, Recruiting

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: New York NY, Augusta GA, Grand Rapids MI, Chicago IL,
Sponsor: National Cancer Institute LAO

Sex: All

Age: 0+

Code: NCT02474160

Recruiting