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Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc

for
Glioblastoma Multiforme
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05366179

Phase1, Recruiting

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

for
Malignant Brain Neoplasm, Malignant Glioma
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT03510208

Phase1, Phase2, Recruiting

Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers

for
Metastatic Malignant Solid Neoplasm
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06606990

Phase1, Recruiting

Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma

for
Malignant Melanoma, Neoplasm Metastasis
Location: Houston TX
Sponsor: Introgen Therapeutics

Sex: All

Age: 18+

Code: NCT00116363

Phase2, Recruiting

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

for
Obesity, Malignant Neoplasm
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 13 - 30

Code: NCT04453072

Recruiting

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Palbociclib and Pembrolizumab In Central Nervous System Metastases

for
Metastatic Malignant Neoplasm to Brain,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT02896335

Phase2, Recruiting

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

for
Glioma, Malignant Brain Neoplasm, Meningioma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06650163

Phase1, Recruiting

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

for
Leukemia, Acute Leukemia, Acute Lymphoid Leukemia,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 6+

Code: NCT07634653

Recruiting

Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors

for
Thoracic Neoplasms, Lumbar Neoplasm
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07479199

Recruiting

Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers

for
Advanced Malignant Solid Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05691517

Phase1, Recruiting

Effect of A Multimodal Exercise Intervention on Chemotherapy Uptake in Newly Diagnosed Pediatric and AYA Sarcoma Patients

for
Sarcoma
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 12 - 39

Code: NCT07359911

Recruiting

Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis

for
Malignant Brain Neoplasm,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07339085

Recruiting

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Deerfield Beach FL, Coral Gables FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04585958

Phase1, Recruiting

Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes

for
Hereditary Malignant Neoplasm, Hereditary Neoplastic Syndrome
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT06927947

Recruiting

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

for
Glioblastoma, Glioblastoma, IDH-Wildtype, Gliosarcoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07089641

Phase1, Recruiting

Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients

for
Glioblastoma
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07461948

Phase3, Recruiting

Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

for
Malignant Neoplasm
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT02280161

Recruiting

Rhenium Re 188 P2045 in Patients With Lung Cancer Who Have Received or Refused to Receive Prior Chemotherapy

for
Lung Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Baltimore MD, Iowa City IA
Sponsor: Andarix Pharmaceuticals

Sex: All

Age: 21+

Code: NCT00100256

Phase1, Phase2, Recruiting

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

for
Locally Advanced Malignant Solid Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03907475

Phase2, Recruiting

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

for
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT01137643

Recruiting