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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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Study of AVZO-021 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor, HR+/HER2- Breast Cancer,
Location: New Haven CT, Mineola NY, New York NY, Philadelphia PA,
Sponsor: Avenzo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05867251

Phase1, Phase2, Recruiting

The Minimalist Trial-2

for
HPV-Related Oropharynx Squamous Cell Carcinoma
Location: St Louis MO, Fargo ND, Sioux Falls SD
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06702033

Phase2, Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: The Bronx NY, Newark NJ, New Brunswick NJ, Baltimore MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05172245

Phase1, Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

for
Breast Cancer, Gastric Cancer, Esophageal Cancer,
Location: New York NY, Nashville TN, Houston TX, Dallas TX,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06695845

Phase2, Recruiting

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC),
Location: Boston MA, Sarasota FL, Grand Rapids MI, Nashville TN,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06784193

Phase1, Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Gloucester MA, Beverly MA, Peabody MA, Burlington MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06058377

Phase3, Recruiting

Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy

for
Breast Cancer, Hyperinsulinism, HER2-negative Breast Cancer
Location: New Haven CT
Sponsor: Yale University

Sex: Female

Age: 18+

Code: NCT05989347

Phase1, Recruiting

Optimizing Influenza Vaccination in Surgical Oncology Patients

for
Influenza
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT01698177

Recruiting

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, HER2 Mutation
Location: Montreal, Fort Lauderdale FL, Toronto, Pittsburgh PA,
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06452277

Phase3, Recruiting

Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI

for
HER2-positive Breast Cancer
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 18+

Code: NCT04332588

Phase1, Recruiting

Sacituzumab Govitecan In TNBC

for
Invasive Breast Cancer, Triple Negative Breast Cancer,
Location: Danvers MA, Boston MA, Newton MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT04230109

Phase2, Recruiting

Phase Ib Study of Axatilimab in Combination With Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer

for
Breast Cancer, PALB2-Mutated Breast Carcinoma,
Location: Boston MA, Rochester MN
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06488378

Phase1, Recruiting

ATEMPT 2.0: Adjuvant T-DM1 vs TH

for
Breast Cancer, HER2-positive Breast Cancer
Location: Brewer ME, Scarborough ME, Weymouth MA, Danvers MA,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04893109

Phase2, Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

for
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer,
Location: Boston MA, Lebanon NH, New York NY, New Brunswick NJ,
Sponsor: Iambic Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06253871

Phase1, Recruiting

Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer

for
HER2-positive Breast Cancer, Advanced Breast Cancer
Location: Boston MA, Miami FL
Sponsor: University of Miami

Sex: Female

Age: 18+

Code: NCT06123988

Recruiting

The Effects of Endotracheal Suctioning on Pain and Serum Markers

for
Intensive Care Unit ICU, Intubation, Critical Illness,
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 18+

Code: NCT06692400

Recruiting

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

for
Carcinoma, Non-Small Cell Lung,
Location: Boston MA, Newton MA, Shirley NY, Riverhead NY,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT04389632

Phase1, Recruiting

Prevención en Sus Manos: Feasibility of a Novel Community-Based Strategy to Improve Access to Cervical Cancer Screening

for
HPV
Location: Houston TX, Austin TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06109870

Recruiting

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

for
Salivary Gland Cancer, HER2 Gene Mutation
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04620187

Phase2, Recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer

for
Breast Cancer, HER2-positive Breast Cancer
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT06441890

Phase2, Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial