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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for
Gastroesophageal-junction Cancer, Monoclonal Antibody,
Location: Sayre PA, West Palm Beach FL, Pompano Beach FL,
Sponsor: Shanghai Henlius Biotech

Sex: All

Age: 18+

Code: NCT06532006

Phase3, Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for
Advanced Solid Tumor, Advanced Malignant Neoplasm,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: PMV Pharmaceuticals, Inc

Sex: All

Age: 12+

Code: NCT04585750

Phase1, Phase2, Recruiting

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

for
Advanced HR+/HER2- Breast Cancer,
Location: Boston MA, New York NY, Montreal, Toronto,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06726148

Phase1, Phase2, Recruiting

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

for
Advanced Breast Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT04090567

Phase2, Recruiting

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for
Locoregional Recurrence,
Location: Boston MA, New York NY, New Brunswick NJ, Hershey PA,
Sponsor: Oana Danciu

Sex: All

Age: 18+

Code: NCT05467891

Phase2, Recruiting

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Flu Infection at UPHS

for
Influenza Human
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT06807840

Recruiting

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

for
Breast Cancer, Breast Neoplasm, Breast Cancer Female,
Location: Houston TX
Sponsor: Baylor Breast Care Center

Sex: All

Age: 18+

Code: NCT05020860

Phase2, Recruiting

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06323460

Phase2, Recruiting

Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery

for
Estrogen Receptor-Positive Breast Carcinoma,
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: Female

Age: 18+

Code: NCT06450873

Phase2, Recruiting

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

for
HER2-positive Advanced Solid Tumor
Location: Boston MA, Shirley NY, Lake Success NY, New York NY,
Sponsor: DualityBio Inc.

Sex: All

Age: 18+

Code: NCT05150691

Phase1, Phase2, Recruiting

NearWave Optical Molecular Monitoring

for
Breast Cancer, HER2-positive Breast Cancer,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: Female

Age: 18+

Code: NCT06744465

Recruiting

Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients

for
Pediatric Cancer
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 2 - 21

Code: NCT04948619

Phase2, Recruiting
New

IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy

for
Recurrent Prostate Cancer, Prostate Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18 - 70+

Code: NCT07686380

Phase2, Recruiting
New

A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

for
Pneumococcal Disease
Location: Milford CT, Somers Point NJ, Wilmington NC,
Sponsor: Pfizer

Sex: All

Age: 18 - 49

Code: NCT07794748

Phase3, Recruiting
New

A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised Adults

for
Respiratory Syncytial Virus (RSV)
Location: New York NY, Washington D.C. DC, Rochester NY,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07768345

Phase3, Recruiting

Adolescents' Response to Hepatitis B Vaccine Booster Dose

for
Hepatitis B
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 16 - 19

Code: NCT01341275

Recruiting

A Feasibility Study Utilizing Immune Recall to Increase Response to Checkpoint Therapy

for
Melanoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05077137

Phase1, Recruiting

KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC

for
Non-Small Cell Lung Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18 - 70+

Code: NCT05254184

Phase1, Recruiting

HPV Vaccine, Imiquimod, and Metformin Combination Trial

for
Cervical Carcinoma, Vaginal Carcinoma, Vulvar Carcinoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: Female

Age: 18 - 64

Code: NCT06686043

Phase2, Recruiting

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

for
Ductal Carcinoma in Situ
Location: Pittsburgh PA
Sponsor: Finn, Olivera, PhD

Sex: Female

Age: 18+

Code: NCT06218303

Phase1, Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial