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Brain Cancer Clinical Trials

Browse 315 brain cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

for
Cancer, All Types, Cancer of Liver, Cancer of Stomach,
Location: Gainesville GA
Sponsor: SpeciCare

Sex: All

Age: 0 - 70+

Code: NCT03896958

Recruiting

Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases

for
Brain (Nervous System) Cancers, Brain Metastasases, SRS
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07162246

Phase2, Recruiting

Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases

for
Breast Cancer, Triple Negative Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06238921

Phase1, Phase2, Recruiting

Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling

for
Breast Cancer
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT04965064

Phase2, Recruiting

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05376878

Recruiting

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A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

for
HER2-negative Breast Cancer Patients With Brain Metastases
Location: Stony Brook NY, Baltimore MD, Augusta GA, Chicago IL,
Sponsor: Biostar Pharma, Inc.

Sex: All

Age: 18+

Code: NCT06764940

Phase2, Recruiting

Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery

for
Breast Cancer
Location: Toronto
Sponsor: University of Toronto

Sex: Female

Age: 18 - 65

Code: NCT04616300

Recruiting

Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients

for
Metastatic Breast Cancer, Brain Metastases
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: Female

Age: 19 - 70+

Code: NCT03449238

Phase1, Phase2, Recruiting

Short-term Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer

for
Breast Cancer Females
Location: Toronto
Sponsor: University of Toronto

Sex: Female

Age: 0+

Code: NCT06781762

Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

for
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer,
Location: Boston MA, Lebanon NH, New York NY, New Brunswick NJ,
Sponsor: Iambic Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06253871

Phase1, Recruiting

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

for
Lung Cancer, NSCLC, Brain Metastases
Location: Columbus OH, Aurora CO, Stanford CA
Sponsor: Joshua Palmer

Sex: All

Age: 18+

Code: NCT05987644

Phase1, Phase2, Recruiting

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Charlottesville VA, Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: Female

Age: 18+

Code: NCT04348747

Phase2, Recruiting

Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer

for
Impaired Cognition, Chemo-brain, Breast Cancer
Location: Salem MA, Boston MA
Sponsor: Massachusetts General Hospital

Sex: Female

Age: 60+

Code: NCT02290834

Recruiting

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

for
Lung Cancer, Lung Cancer Metastatic, Brain Metastases,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05419076

Phase2, Recruiting

Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer

for
Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07357298

Phase3, Recruiting

A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain

for
Non Small Cell Lung Cancer Metastatic
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06741085

Phase2, Recruiting
New

B7-H3.CD28Z.CART in CNS Neoplasms

for
Central Nervous System Neoplasms, Brain Tumor,
Location: Boston MA
Sponsor: Robbie Majzner

Sex: All

Age: 2 - 21

Code: NCT07390539

Phase1, Recruiting
New

Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases

for
Breast Cancer, Breast Carcinoma, Cancer of the Breast,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT07619534

Recruiting

Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy

for
Head and Neck Squamous Cell Carcinoma, Brain Metastases
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05996432

Early_phase1, Recruiting

Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)

for
Medulloblastoma, Childhood,
Location: Washington D.C. DC
Sponsor: Children's National Research Institute

Sex: All

Age: 1 - 30

Code: NCT06193759

Phase1, Recruiting