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Brain Cancer Clinical Trials

Browse 315 brain cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Familial Investigations of Childhood Cancer Predisposition

for
Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT03050268

Recruiting

18F-DOPA II - PET Imaging Optimization

for
Congenital Hyperinsulinism, Neuroblastoma, Parkinson Disease,
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 0+

Code: NCT04706910

Phase3, Recruiting

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

for
Melanoma (Skin Cancer), Breast Cancer, Brain Metastasases
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06545682

Phase1, Recruiting

Brodalumab in the Treatment of Immune-Related Adverse Events

for
Breast Cancer, Esophageal Cancer, Kidney Cancer, Lung Cancer,
Location: New York NY
Sponsor: Brian Henick, MD

Sex: All

Age: 18+

Code: NCT06673329

Phase1, Recruiting

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

for
Liver Cancer, Rhabdomyosarcoma, Malignant Rhabdoid Tumor,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 1 - 21

Code: NCT04715191

Phase1, Recruiting

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Cancer Genetic Testing in Ethnic Populations

for
Breast Carcinoma, Carcinoma of Unknown Primary,
Location: Jacksonville FL, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04475640

Recruiting

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for
Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06810544

Phase1, Phase2, Recruiting

Study of Olutasidenib and Temozolomide in HGG

for
High Grade Glioma, Astrocytoma, Astrocytoma, Grade III,
Location: Durham NC, Miami FL, Columbus OH, Cincinnati OH,
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 12 - 39

Code: NCT06161974

Phase2, Recruiting

Phase I Human Analytics (HALO) Study

for
Cardiovascular Diseases, Cancer, Dementia,
Location: Indian Wells CA
Sponsor: HALO Diagnostics

Sex: Male

Age: 45 - 70+

Code: NCT05423860

Recruiting

Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures

for
Diabetes, Cancer, Multiple Sclerosis, Arthritis,
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18+

Code: NCT02777060

Recruiting

Radiologic Pathologic Correlation of Advanced MR Imaging to Guide the Biopsy of Cerebral Malignancies

for
Brain Lesion
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03458676

Recruiting

Exploring the Feasibility of Cerebrospinal Fluid (CSF) and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and Primary Central Nervous System (CNS) Tumours: A Pilot Study

for
Solid Tumor Malignancies, Brain Metastasases,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07476781

Recruiting

Improve Cancer-related Cognitive Impairment

for
Gynecologic Cancer, Chemotherapy Effect, Chemo-brain,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 18 - 70+

Code: NCT05864274

Recruiting

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

for
Small-cell Lung Cancer, Brain Metastases
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18+

Code: NCT07175077

Recruiting

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

for
Childhood Cancer, Childhood Solid Tumor, Childhood Brain Tumor,
Location: Montreal, Toronto, Vancouver
Sponsor: Australian & New Zealand Children's Haematology/Oncology Group

Sex: All

Age: 0 - 21

Code: NCT06208657

Phase1, Phase2, Recruiting

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

for
Estrogen-receptor-positive Breast Cancer,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT06062498

Phase2, Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for
Atypical Teratoid/Rhabdoid Tumor,
Location: Hartford CT, Hackensack NJ, Hershey PA, Miami FL,
Sponsor: Milton S. Hershey Medical Center

Sex: All

Age: 0 - 26

Code: NCT06465199

Phase1, Phase2, Recruiting

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

for
Advanced Cancers (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Mets) With Specific Mutations (Homologous Recombination Deficiency),
Location: New Haven CT, New York NY, Houston TX, Sacramento CA
Sponsor: Duke Street Bio Ltd

Sex: All

Age: 18+

Code: NCT06458712

Phase1, Recruiting

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

for
Medulloblastoma, Central Nervous System Embryonal Tumor,
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 1 - 30

Code: NCT07087002

Phase1, Recruiting

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

for
Central Nervous System Cancer, Brain Metastases
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07462507

Phase2, Recruiting