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Brain Cancer Clinical Trials

Browse 315 brain cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility Study

for
HER2-positive Breast Cancer, LMD
Location: Ottawa, Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06016387

Phase2, Recruiting

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

for
Endometrial Cancer, ARID1A Gene Mutation,
Location: Boston MA
Sponsor: Panagiotis Konstantinopoulos, MD, PhD

Sex: Female

Age: 18+

Code: NCT06518564

Phase2, Recruiting

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

for
Estrogen Receptor Negative, HER2 Positive Breast Carcinoma,
Location: Voorhees Township NJ, Pittsburgh PA, Charlotte NC,
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 30+

Code: NCT02945579

Recruiting

Targeted Pediatric High-Grade Glioma Therapy

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma,
Location: Washington D.C. DC, Durham NC, Miami FL, Columbus OH,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 39

Code: NCT05839379

Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

for
Pediatric Solid Tumor, Osteosarcoma, Rhabdomyosarcoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT04897321

Phase1, Recruiting

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Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

for
Non Small Cell Lung Cancer, NSCLC, KRAS G12C
Location: Richmond VA, Charlottesville VA, Columbus OH
Sponsor: Ryan Gentzler, MD

Sex: All

Age: 18+

Code: NCT06248606

Phase2, Recruiting

NYSCF Scientific Discovery Biobank

for
ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease,
Location: New York NY
Sponsor: New York Stem Cell Foundation Research Institute

Sex: All

Age: 0+

Code: NCT06203106

Recruiting

European Prospective Investigation Into Childhood Cancer

for
Acute Lymphoblastic Leukemia, Brain Tumor
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 3 - 21

Code: NCT05375617

Recruiting

Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

for
Autism Spectrum Disorder, Mitochondrial Pathology, Epilepsy,
Location: Brooklyn NY, Phoenix AZ
Sponsor: Southwest Autism Research & Resource Center

Sex: All

Age: 0 - 18

Code: NCT04322734

Recruiting

Markers of Prognosis and Response to Therapy in Patients With Metastatic Brain Tumors Undergoing Stereotactic Radiosurgery (SRS)

for
Metastatic Brain Tumor
Location: Seattle WA
Sponsor: Swedish Medical Center

Sex: All

Age: 19 - 70+

Code: NCT01908179

Recruiting

Radiologic Pathologic Correlation of Imaging to Distinguish True Progression From Pseudoprogression in Brain Malignancies

for
Brain Malignancies, Pseudoprogression
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06199479

Phase1, Recruiting

Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas

for
Primary Central Nervous System Lymphoma,
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05681195

Phase2, Recruiting

Establishing a Tumor Registry for Patients With Neuroendocrine Carcinoma of the Cervix

for
Cervical Large Cell Neuroendocrine Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT04723095

Recruiting

Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI

for
Cancer Related Cognitive Difficulties, Breast Cancer Female
Location: Rochester NY
Sponsor: University of Rochester

Sex: Female

Age: 21+

Code: NCT03137095

Recruiting

Feasibility/Acceptability of Attentional-Control Training in Survivors

for
Pediatric Cancer, Pediatric ALL, Pediatric Brain Tumor,
Location: Washington DC
Sponsor: Children's National Research Institute

Sex: All

Age: 8 - 16

Code: NCT05528939

Recruiting

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

for
Spinal Cord Injuries, Nerve Injury, Pain, Postoperative,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 22 - 70+

Code: NCT04144972

Recruiting

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

for
Solid Tumors, ER+ Breast Cancer,
Location: Detroit MI, St Louis MO, Dallas TX, Salt Lake City UT
Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All

Age: 18+

Code: NCT05490472

Phase1, Phase2, Recruiting

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Miami FL
Sponsor: Florida International University

Sex: All

Age: 0 - 21

Code: NCT05857969

Phase1, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

Virtual Home-based Exercise Intervention (RISE) to Improve Cancer-Related Cognitive Impairment and Gut Microbiome in Adolescent and Young Adult Brain Tumor Survivors

for
Cancer-related Cognitive Dysfunction, Primary Brain Neoplasm
Location: Atlanta GA, Houston TX
Sponsor: Emory University

Sex: All

Age: 15 - 39

Code: NCT06799481

Recruiting