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Colorectal Cancer Clinical Trials

Browse 515 colorectal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

for
Locally Advanced Colorectal Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06307548

Phase1, Phase2, Recruiting

A Cross-sectional Partnership to Improve Prevention and Health Equity Among African Americans

for
Colorectal Cancer, Prevention
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 45 - 70+

Code: NCT05903885

Recruiting

Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

for
Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06617858

Phase2, Recruiting

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

for
Colorectal Cancer, Endometrial Cancer,
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT06096688

Recruiting

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

for
Advanced Solid Tumors, MSI-H or dMMR Advanced Solid Tumors,
Location: Lake Success NY, New York NY, Morristown NJ, Tamarac FL,
Sponsor: Eikon Therapeutics

Sex: All

Age: 18+

Code: NCT07262619

Phase1, Phase2, Recruiting

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Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma,
Location: Toronto, Dallas TX, San Antonio TX
Sponsor: Auricula Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07148128

Phase1, Phase2, Recruiting

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

for
Refractory Metastatic Colorectal Cancer
Location: Tampa FL, New Orleans LA, Fairway KS, Salt Lake City UT,
Sponsor: Delcath Systems Inc.

Sex: All

Age: 18+

Code: NCT06607458

Phase2, Recruiting

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06959550

Phase2, Recruiting

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

for
Cancer, Breast Cancer, Colorectal Cancer, Sarcoma, Lymphoma,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 39

Code: NCT06371768

Recruiting

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

for
Colorectal Cancer, CRC (Colorectal Cancer), Cancer Cachexia
Location: New York NY, Baltimore MD, Richmond VA, Margate FL,
Sponsor: NGM Biopharmaceuticals, Inc

Sex: All

Age: 18+

Code: NCT07033026

Phase2, Recruiting

FITting Non-invasive Tests in Lynch Syndrome Surveillance

for
Colorectal Cancer
Location: New York NY, Ann Arbor MI, Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 20 - 70+

Code: NCT06898996

Recruiting

Impact of the Enhanced Recovery After Surgery System for Colorectal Surgery

for
ColoRectal Cancer and Inflammatory Bowel Disease
Location: Little Rock AR
Sponsor: University of Arkansas

Sex: All

Age: 18+

Code: NCT02997293

Recruiting

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Raleigh NC, Tampa FL, Detroit MI, St Louis MO,
Sponsor: MOMA Therapeutics

Sex: All

Age: 18+

Code: NCT06974110

Phase1, Recruiting

Trial of ProAgio in Advanced/Metastatic Colorectal Cancer

for
Advanced Colorectal Cancer, Metastatic Colorectal Cancer
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 19+

Code: NCT06867822

Phase1, Recruiting

Intravital Microscopy in Human Solid Tumors

for
Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03823144

Recruiting

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

for
Colon Cancer, Rectal Cancer, Colorectal Cancer,
Location: Wynnewood PA, Norfolk VA, Columbia MD, Salem VA,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 18+

Code: NCT07011576

Phase2, Recruiting

The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities

for
Colorectal Cancer
Location: West Lafayette IN
Sponsor: Purdue University

Sex: All

Age: 45 - 70+

Code: NCT07086833

Recruiting

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: New Haven CT, Cleveland OH, Grand Rapids MI, Houston TX
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07079631

Phase1, Phase2, Recruiting

TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

for
Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05343013

Phase2, Recruiting

Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

for
Colorectal Cancer, Liver Metastases, Liver Cancer
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07044362

Recruiting