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Colorectal Cancer Clinical Trials

Browse 515 colorectal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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FeaturedActive & Responsive

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for
Metastatic Colorectal Cancer
Location: Port Jefferson Station NY, New Haven CT,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT04929223

Phase1, Recruiting
Featured

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Boston MA, New Haven CT, Montreal, Fairfax VA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06820463

Phase2, Recruiting
Featured

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

for
Colorectal Cancer
Location: New Haven CT, Lake Success NY, East Brunswick NJ,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07525206

Phase3, Recruiting
Active & Responsive

GUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel Adenocarcinomas

for
Colorectal Cancer, Small Bowel Adenocarcinoma
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT07417488

Phase1, Recruiting
Active & Responsive

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Location: Rockport ME, Belfast ME, Damariscotta ME, Augusta ME,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07018869

Phase3, Recruiting

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Active & Responsive

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

for
Cancer, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: Alterome Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06835569

Phase1, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, Non-Small Cell Lung,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06682793

Phase1, Phase2, Recruiting
Active & Responsive

Increasing Germline Genetic Testing for Patients With Cancer

for
Hereditary Pancreatic Cancer, Conditions or Focus of Study,
Location: Danville PA, Durham NC, Salisbury NC, Orlando FL,
Sponsor: Josh Peterson

Sex: All

Age: 0+

Code: NCT07307664

Recruiting
Active & ResponsiveNew

Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease

for
Colorectal Cancer
Location: Toms River NJ, Edison NJ, East Brunswick NJ, Monroe NJ,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT07750158

Phase3, Recruiting
Active & ResponsiveNew

Regorafenib (Reg) and Lorigerlimab (Lor), RELO Regimen, in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy [ReLOAD Trial]

for
Colorectal Cancer, Regorafenib, High Risk Patients
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07071961

Phase2, Recruiting
Active & ResponsiveNew

Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients

for
Colorectal Cancer
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT07403981

Recruiting
Active & Responsive

Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs

for
Lung Cancer Diagnosis, Colorectal Cancer (Diagnosis),
Location: Jamaica NY, New York NY, Brooklyn NY, Staten Island NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06559059

Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase1, Phase2, Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

for
Colorectal Cancer Screening, Colorectal Cancer Metastatic,
Location: Morrisville NC
Sponsor: Mainz Biomed

Sex: All

Age: 18+

Code: NCT06864338

Recruiting
Active & Responsive

Reducing Metabolic Dysregulation in Dyads

for
Colorectal Cancer, Inflammation, Nutrition Related Cancer
Location: Columbia SC
Sponsor: University of South Carolina

Sex: All

Age: 9 - 55

Code: NCT06117241

Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase1, Phase2, Recruiting
Active & Responsive

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

for
Colon Cancer, dMMR Colorectal Cancer
Location: Madison WI, Iowa City IA
Sponsor: University of Iowa

Sex: All

Age: 18+

Code: NCT05239546

Phase2, Recruiting
Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase1, Phase2, Recruiting
Active & Responsive

A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation

for
Colorectal Cancer, Advanced Adenocarcinoma
Location: Raonoke VA
Sponsor: Universal Diagnostics

Sex: All

Age: 45 - 70+

Code: NCT06059963

Recruiting