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Colorectal Cancer Clinical Trials

Browse 515 colorectal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

for
Stage IV Esophageal Adenocarcinoma,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT04221893

Recruiting

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for
Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer,
Location: Boston MA, New York NY, Fairfax VA, Pittsburgh PA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06128551

Phase1, Phase2, Recruiting

A Study of Mental Health Care in People With Cancer

for
Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 65+

Code: NCT06037954

Recruiting

Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy

for
Metastatic Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05985954

Phase1, Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Colorectal Cancer
Location: New Brunswick NJ, Toronto, Atlanta GA, Ann Arbor MI,
Sponsor: Vividion Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06004245

Phase1, Recruiting

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A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

for
Breast Cancer, Gastric Cancer, Esophageal Cancer,
Location: New York NY, Nashville TN, Houston TX, Dallas TX,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06695845

Phase2, Recruiting

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

for
Metastatic Colorectal Cancer, KRAS G12C Mutations
Location: Boston MA, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06412198

Phase1, Phase2, Recruiting

A Study of IBI363 in Subjects with Advanced Solid Malignancies

for
Melanoma, Non-small Cell Lung Cancer, Colorectal Cancer,
Location: Plantation FL, Ocala FL, Dearborn MI, Troy MI,
Sponsor: Innovent Biologics (Suzhou) Co. Ltd.

Sex: All

Age: 18+

Code: NCT06281678

Phase2, Recruiting

A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors

for
Solid Tumor, Adult, Colorectal Cancer,
Location: Houston TX
Sponsor: Crossignal Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06598007

Phase1, Phase2, Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Boston MA, New York NY, Baltimore MD, Fairfax VA,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05379985

Phase1, Phase2, Recruiting

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

for
Bladder Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 18+

Code: NCT03740256

Phase1, Recruiting

Lead-212 PSV359 Therapy for Patients With Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Gastric Cancer,
Location: Miami FL, Pittsburgh PA, Columbus OH, Lexington KY,
Sponsor: Perspective Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06710756

Phase1, Phase2, Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

for
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer,
Location: Boston MA, Lebanon NH, New York NY, New Brunswick NJ,
Sponsor: Iambic Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06253871

Phase1, Recruiting

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for
Advanced Solid Tumors With KRAS G12C Mutations,
Location: Boston MA, Philadelphia PA, Fairfax VA, Detroit MI,
Sponsor: Frontier Medicines Corporation

Sex: All

Age: 18+

Code: NCT06244771

Phase1, Phase2, Recruiting

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

for
Metastatic Uveal Melanoma, Cutaneous Melanoma,
Location: Philadelphia PA, Durham NC, Cincinnati OH, Nashville TN,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT03947385

Phase1, Phase2, Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

for
Advanced Esophageal Squamous Cell Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06265285

Phase2, Recruiting

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for
KRAS G12C Mutation, KRAS G12S Mutation,
Location: Boston MA, Philadelphia PA, Fairfax VA, Jacksonville FL,
Sponsor: Kumquat Biosciences Inc.

Sex: All

Age: 18+

Code: NCT06720987

Phase1, Recruiting

Outreach and Choice in Colorectal Cancer Screening

for
Colorectal Cancer Screening
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 45 - 70+

Code: NCT04940442

Recruiting

Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis

for
Metastatic Colorectal Cancer
Location: Montreal
Sponsor: Alethia Biotherapeutics

Sex: All

Age: 18+

Code: NCT06225843

Phase2, Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for
Metastatic Colorectal Cancer
Location: Durham NC, Toronto, Brampton, Jacksonville FL,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT06252649

Phase3, Recruiting