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Colorectal Cancer Clinical Trials

Browse 515 colorectal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

for
Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma,
Location: Scottsdale AZ
Sponsor: VM Discovery, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07636785

Phase1, Phase2, Recruiting
Active & Responsive

Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

for
Colorectal Cancer, Metastatic Colorectal Cancer (CRC)
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT07759921

Recruiting
Active & Responsive

Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

for
Cascade Testing, Lynch Syndrome, Decision Making,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT07106359

Recruiting
Active & Responsive

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

for
Colorectal Cancer
Location: New York NY, East Brunswick NJ, Fairfax VA,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07659795

Phase2, Recruiting
Active & Responsive

TCR1188-ABC Cells in KRAS-mutated Cancers

for
Cholangiocarcinoma, Colorectal Cancer,
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07594067

Phase1, Recruiting

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Active & Responsive

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

for
Metastatic Colorectal Adenocarcinoma,
Location: Baltimore MD, Washington D.C. DC, Atlanta GA, Aurora CO
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07147231

Phase1, Phase2, Recruiting
Active & Responsive

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Norwich CT, Fairfax VA, Nashville TN, Saint Paul MN,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07397338

Phase1, Phase2, Recruiting
Active & Responsive

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

for
Castration-Resistant Prostate Cancer (CRPC), Colorectal Cancer,
Location: Dothan AL, Grand Rapids MI, Omaha NE
Sponsor: Radiopharm Theranostics, Ltd

Sex: All

Age: 18+

Code: NCT07189871

Phase1, Phase2, Recruiting
Active & Responsive

Testing the Feasibility of a Virtual Application to Support Breast and Colorectal Cancer Survivors

for
Breast Cancer Survivor, Colorectal Cancer Survivors
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18+

Code: NCT07312786

Recruiting
Active & Responsive

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for
Colorectal Cancer, Colorectal Cancer (CRC),
Location: Fairfax VA, Jacksonville FL, Atlanta GA,
Sponsor: Cartography Biosciences

Sex: All

Age: 18+

Code: NCT07321106

Phase1, Recruiting
Active & Responsive

The Florida ASCENT Study

for
Cancer, Food Deprivation, Food Habits, Food Selection,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT07042243

Recruiting
Active & Responsive

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

for
Left-sided Colorectal Cancer
Location: Savannah GA, Warner Robins GA, Indianapolis IN,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07702032

Phase3, Recruiting
Active & Responsive

Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver Metastasis

for
Colorectal Adenocarcinoma Metastatic in the Liver,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07764497

Phase2, Recruiting
Active & Responsive

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

for
Colorectal Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07281768

Phase2, Recruiting
Active & Responsive

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

for
Colorectal Cancer
Location: New York NY, Baltimore MD, Pittsburgh PA, Louisville KY,
Sponsor: Exero Medical Ltd.

Sex: All

Age: 21+

Code: NCT07337590

Recruiting
Active & Responsive

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

for
Solid Tumor, Non-Small-Cell Lung Cancer,
Location: New York NY, Hackensack NJ, Fairfax VA, Buffalo NY,
Sponsor: Astellas Pharma Inc

Sex: All

Age: 18+

Code: NCT07094204

Phase1, Recruiting
Active & Responsive

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

for
Colorectal Cancer
Location: York PA, Bethesda MD, Goldsboro NC, Canton OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05234177

Recruiting
Active & Responsive

Protein Needs Study

for
Colorectal Cancer, Breast Cancer
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 45 - 70+

Code: NCT04144907

Recruiting
Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase1, Phase2, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Pennington NJ, Philadelphia PA, Newark DE, Baltimore MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting