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Colorectal Cancer Clinical Trials

Browse 515 colorectal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for
Non-small Cell Lung Cancer, Histiocytic Neoplasm, Histiocytosis,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT05786924

Phase1, Phase2, Recruiting
Active & Responsive

Building Connections

for
Cancer Colorectal, Cancer Cervix, Depression, Anxiety, Obesity
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT07091032

Recruiting
Active & Responsive

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

for
Colorectal Neoplasms, Breast Neoplasms, Head and Neck Neoplasms,
Location: Toms River NJ, Jersey City NJ, Belleville NJ, Newark NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT07158164

Recruiting
Active & Responsive

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor Malignancies, Colorectal Carcinoma,
Location: Philadelphia PA, Fairfax VA, Orlando FL,
Sponsor: Tasca Therapeutics

Sex: All

Age: 18+

Code: NCT07030257

Phase1, Phase2, Recruiting
Active & Responsive

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm,
Location: Boston MA, New York NY, Toronto, Hamilton, Tampa FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07114601

Phase1, Recruiting

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Active & Responsive

Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC

for
Colorectal Carcinoma Metastatic in the Liver
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT06555133

Phase2, Recruiting
Active & Responsive

Regular Diet After Colorectal Surgery

for
Colorectal, Diet Habits, Surgery, Post-operative Care
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT07540845

Recruiting
Active & Responsive

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for
Intestinal Neoplasms, Gastrointestinal Neoplasms,
Location: Topsham ME, Westbrook ME, Boston MA, Newton MA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222800

Phase3, Recruiting
Active & Responsive

Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers

for
Stage I Colon Cancer AJCC v8, Stage I Rectal Cancer AJCC v8,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06746012

Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

for
Cancer, Breast Cancer, Lung Cancer, Colon Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03702309

Recruiting
Active & ResponsiveNew

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07795749

Phase2, Recruiting
Active & Responsive

Improving Care for Rural Patients With Solid Tumors

for
Lung Cancer, Head and Neck Cancer, Thyroid Cancer,
Location: Greeley CO, Aurora CO, Loveland CO, Fort Collins CO,
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT04916990

Recruiting
Active & Responsive

The Cancer of the Pancreas Screening-5 CAPS5)Study

for
Pancreas Cancer, Peutz-Jeghers Syndrome (PJS), Gene Mutation,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT02000089

Phase3, Recruiting
Active & Responsive

Bundled Cancer Screening and Genetic Services Navigation

for
Breast Cancer Screening, Colon Cancer Screening,
Location: Newark DE, Washington D.C. DC
Sponsor: Georgetown University

Sex: Female

Age: 45 - 70+

Code: NCT07228000

Recruiting
Active & Responsive

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

for
Prostate Cancer Castration-resistant Prostate Cancer,
Location: East Brunswick NJ, Fairfax VA, Grand Rapids MI,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT07145255

Phase1, Phase2, Recruiting
Active & Responsive

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

for
Localized Colon Carcinoma, Stage IIB Colon Cancer AJCC v8,
Location: Johns Creek GA, Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT07140679

Phase2, Recruiting
New

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

for
Metastatic Appendix Carcinoma, Metastatic Colorectal Carcinoma,
Location: Goodyear AZ
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07271355

Phase3, Recruiting
New

GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer

for
Pancreatic Cancer, Colorectal Cancer, Hepatocellular Carcinoma
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT07627191

Early_phase1, Recruiting
New

A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer

for
Colorectal Cancer (Locally Advanced or Metastatic)
Location: Faifax VA, Houston TX
Sponsor: SOTIO Biotech a.s.

Sex: All

Age: 18+

Code: NCT07693751

Phase1, Phase2, Recruiting