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Esophageal Cancer Clinical Trials

Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

for
Advanced Esophageal Squamous Cell Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06265285

Phase 2, Recruiting
New

Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)

for
Head and Neck Cancer, Non-Small Cell Lung Cancer,
Location: Lexington KY
Sponsor: Mark Bernard

Sex: All

Age: 18 - 70+

Code: NCT07770100

Phase 2, Recruiting

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

for
Esophageal Cancer, Head and Neck Cancer, Lung Cancer,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 21 - 70+

Code: NCT00900419

Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for
Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer,
Location: Charleston SC, Portland OR, Duarte CA
Sponsor: Adela, Inc

Sex: All

Age: 40+

Code: NCT05366881

Recruiting

Resilience and Equity in Aging, Cancer, and Health (REACH)

for
Gastric Cancer, Colon Cancer, Esophageal Cancer, Rectal Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 65+

Code: NCT04674267

Recruiting

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A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

for
Advanced/Metastatic Solid Tumors, Colorectal Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Syracuse NY,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT03526835

Phase 1, Phase 2, Recruiting

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

for
Esophageal Cancer Surgery, Esophagectomy,
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT06721520

Phase 2, Phase 3, Recruiting

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

for
Advanced Malignant Solid Neoplasm,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT05705492

Phase 2, Recruiting

A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy in Subjects With Select Advanced Solid Tumors

for
NSCLC (Non-small Cell Lung Cancer), HNSCC, Endometrial,
Location: Fairfax VA, Maumee OH, Portland OR
Sponsor: TwoStep Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07814248

Phase 1, Recruiting

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

for
Lung Cancer (NSCLC), Prostate Cancer, Esophageal Cancer,
Location: Orlando FL, Nashville TN, Houston TX
Sponsor: Phrontline Biopharma

Sex: All

Age: 18+

Code: NCT07181473

Phase 1, Recruiting

Sample Collection for Ongoing Research and Product Evaluation Study

for
Breast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer,
Location: Austin TX
Sponsor: Natera, Inc.

Sex: All

Age: 18+

Code: NCT07318051

Recruiting

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

for
Selected Advanced Solid Tumors, Colorectal Cancer (CRC),
Location: Glen Burnie MD
Sponsor: SK Life Science, Inc.

Sex: All

Age: 18+

Code: NCT07812805

Phase 1, Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for
Ovarian Neoplasms, Breast Neoplasms,
Location: Boston MA, New York NY, Philadelphia PA, Glen Burnie MD,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07213791

Phase 1, Recruiting

DESTINY-PANTUMOUR04

for
Adenocarcinoma (NOS), Anal Cancer, Bladder Cancer,
Location: Philadelphia PA, Wilson NC, Durham NC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07124000

Recruiting

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

for
Gastrointestinal Cancer, Gastric Cancer, Esophageal Cancer,
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT07124351

Phase 4, Recruiting

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

for
Advanced Solid Tumors, MSI-H or dMMR Advanced Solid Tumors,
Location: Lake Success NY, New York NY, Morristown NJ, Tamarac FL,
Sponsor: Eikon Therapeutics

Sex: All

Age: 18+

Code: NCT07262619

Phase 1, Phase 2, Recruiting

The Vanguard Study: Testing a New Way to Screen for Cancer

for
Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma,
Location: Portsmouth VA, Norfolk VA, Bethesda MD, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 45 - 70+

Code: NCT06995898

Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for
Metastatic Solid Tumor, Recurrent Solid Tumor,
Location: Boston MA, New York NY, Cleveland OH, Atlanta GA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06465069

Phase 1, Recruiting

IDOV-Immune for Advanced Solid Tumors

for
Colorectal Cancer, Pancreatic Cancer, Melanoma, Ovarian Cancer,
Location: St Louis MO, Houston TX, San Antonio TX
Sponsor: ViroMissile, Inc.

Sex: All

Age: 18+

Code: NCT06910657

Phase 1, Recruiting

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

for
Bladder Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 18+

Code: NCT03740256

Phase 1, Recruiting